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http://dx.doi.org/10.1001/jamapsychiatry.2021.2127 | DOI Listing |
J Virol
January 2025
Department of Infectious Diseases, Molecular Virology, Section Virus-Host Interactions, Heidelberg University, Medical Faculty Heidelberg, Heidelberg, Germany.
NF-κB essential modulator (NEMO) is critically involved in the induction of interferons (IFNs) and pro-inflammatory cytokines. Hepatitis A virus (HAV) 3C protease was recently identified to cleave NEMO in non-hepatic cells. This study aimed at understanding efficiency and function of HAV 3C-mediated NEMO cleavage in hepatocytes.
View Article and Find Full Text PDFISME J
January 2025
Département de Phytologie (FSAA), IBIS, CRIV - Université Laval - Québec (QC) G1V 0A6 - Canada.
Although the 16S (and 18S) rRNA gene has been an essential tool in classifying prokaryotes, using a single locus to revise bacteria taxonomy can introduce unwanted artifacts. There was a recent proposition to split the Methylobacterium genus, which contains diverse plant-associated strains and is important for agriculture and biotechnology, into two genera. Resting strongly on the phylogeny of 16S rRNA, 11 species of Methylobacterium were transferred to a newly proposed genus Methylorubrum.
View Article and Find Full Text PDFPsychotherapy (Chic)
January 2025
Department of Counseling and Human Development, University of Louisville.
There is a growing consensus that effective psychotherapists and counselors require antioppressive, social-justice-oriented, culturally and structurally responsive training (e.g., Neville et al.
View Article and Find Full Text PDFCureus
December 2024
Faculty of Medicine, University of Patras, Rion, GRC.
General practice/family medicine is a primary healthcare discipline that focuses on providing comprehensive, patient-centered care to individuals and families across their lifespan. This study aimed to assess the implementation of artificial intelligence (AI) in general practice/family medicine regarding the 12 characteristics of its discipline as described in the recently revised European Definition of General Practice/Family Medicine. AI has the potential to revolutionize family medicine practice by improving the accuracy, efficiency, and effectiveness of various clinical tasks.
View Article and Find Full Text PDFCrit Care Med
January 2025
Department of Intensive Care, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.
Objectives: Randomized clinical trials informing clinical practice (e.g., like large, pragmatic, and late-phase trials) should ideally mostly use harmonized outcomes that are important to patients, family members, clinicians, and researchers.
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