SPR sensor used for amitrole detection was prepared without using any modification. Molecularly imprinted SPR sensor enabled high selectivity for amitrole pesticide. Amino acid-based functional monomer MATrp was integrated as a recognition element. Tailor-made SPR sensor enables real-time monitoring of amitrole pesticide. Synthetic recognition sites provided by MATrp were prepared without labeling.
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http://dx.doi.org/10.1002/jmr.2929 | DOI Listing |
Sci Rep
March 2025
Department of Physics, Tarbiat Modares University, P.O Box 14115‑175, Tehran, Iran.
Gold nanorods (GNRs) are valued for their tunable surface plasmon resonance (SPR) and unique optical properties, but precise control over their size and shape remains challenging. Current synthesis techniques often yield polydisperse samples and require high concentrations of cytotoxic surfactants, limiting their biomedical applications. In this study, we introduce a novel electrochemical synthesis method that offers precise control of GNR characteristics by leveraging open circuit potential (OCP) data from colloidal synthesis.
View Article and Find Full Text PDFThe advent of evanescent field based fiber optic biosensor and advancements in nanotechnology has create an excellent opportunity in label-free detection of biomarkers which plays vital role in the early, rapid and accurate diagnosis of acute diseases. In this work, we demonstrate a high sensitive Molybdenum Tungsten Disulfide (MoWS2) coated side polished fiber (SPF) biosensor for accurate and early diagnosis of cardio vascular disease (CVD). The Cardiac Troponins I (cTnI) is identified as a biomarker of interest for early and rapid diagnonis of CVD.
View Article and Find Full Text PDFMikrochim Acta
March 2025
School of Engineering, Deakin University, Geelong, Victoria, 3126, Australia.
This paper presents the design and evaluation of an optimized prism-based surface plasmon resonance (SPR) biosensor for the early detection of various cancer types. The Kretschmann configuration-based SPR sensor integrates multiple novel layers, including silver (Ag), zinc selenide (ZnSe), lead telluride (PbTiO ), and silver nanocomposite layers. The SPR sensor is analyzed with angular interrogation analysis, which utilizes the attenuated total reflection (ATR) approach for investigating the refractive index component and detecting different forms of cancer cells.
View Article and Find Full Text PDFWe propose and demonstrate a compact surface plasmon resonance (SPR) sensor based on an inner wall waveguide fiber (IWWF) for magnetic field sensing. The diameter of the central hole in the IWWF is 65 μm, which is propitious for metal deposition and infiltration of magnetic fluid (MF). We deposit a silver film on the inner surface of the IWWF by employing the silver mirror reaction method, and an evanescent field near the inner wall will excite SPR.
View Article and Find Full Text PDFBiosensors (Basel)
February 2025
SENSAVAN, Instituto de Tecnologías Físicas y de la Información (ITEFI), Consejo Superior de Investigaciones Científicas (CSIC), 28006 Madrid, Spain.
Surface acoustic wave (SAW) sensor technology is a promising approach to diagnosing cancer through the detection of cancer biomarkers due to its high sensitivity, potential label-free operation, and fast response times, and, fundamentally, because it is a non-invasive technique in comparison with the current traditional diagnostic techniques for cancer. This review focuses on this application, and for this purpose, the recent literature on cancer biomarkers detected by this advanced technology has been compiled, including that on volatile organic compounds (VOCs) from exhaled breath and larger biomolecules such as proteins, DNA, and microRNAs in body fluids, which demonstrates its great versatility. The conventional techniques for cancer biomarker detection in biofluids, such as ELISA, PCR, SPR, and UV absorbance, exhibit limitations including high costs, slow response times, a reduced sensitivity, the need for specialized instrumentation, and the requirement for highly trained personnel.
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