Unlabelled: Ciliocytophthoria is a phenomenon where degenerated cells in infections or malignancy can present as ciliated cells on microscopy and so may be confused with ciliated parasitic infection. We present an interesting case of recurrent shortness of breath, misdiagnosed as chronic obstructive pulmonary disease exacerbations leading to unnecessary exposure to antimicrobials and steroids. The case was diagnosed as hyper-infection syndrome. Another finding worth mentioning was that ciliated cells noted on broncho-alveolar lavage were thought to be a co-infection with but were later confirmed as ciliocytophthoria.
Learning Points: Strongyloides hyper-infection syndrome should be considered in the differential diagnosis of a patient from an endemic area presenting with non-resolving respiratory symptoms.Ciliocytophthoria is a type of degenerative process where degenerated cells can appear ciliated on microscopy. appears to be similar but is much larger and has cilia circumferentially compared with ciliocytophthoria which has a polar distribution of cilia.
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http://dx.doi.org/10.12890/2021_002707 | DOI Listing |
Iran J Parasitol
January 2024
Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Background: is one of the neglected tropical diseases. We aimed to verify the genetic diversity of with attention to clinical features of the infection in patients using the 1 gene and DNA sequencing.
Methods: Using parasitological methods, was isolated from stool samples of patients who had been referred to Tehran University of Medical Sciences, Tehran, Iran.
J Assoc Med Microbiol Infect Dis Can
June 2022
Multi-Organ Transplant Program, Division of Infectious Diseases, University Health Network, University of Toronto, Toronto, Ontario, Canada.
Case Presentation: A 63-year-old man with a left single lung transplant for end-stage combined restrictive and obstructive lung disease developed persistent pulmonary infiltrates and recurrent gram-negative bacteremia post-transplant. Bronchoalveolar lavage fluid revealed a nematode on Papanicolau staining compatible with larvae on day 50 post-transplant. Although serology performed post-transplant was negative, a retrospective review of the medical record revealed marked peripheral blood eosinophilia on several occasions before transplantation.
View Article and Find Full Text PDFIndian J Pathol Microbiol
January 2022
Department of Pathology, Dr. D.Y. Patil Medical College and Hospital, Sector 5, Nerul, Navi Mumbai, Maharashtra, India.
Infection with Strongyloides stercoralis, a human pathogenic roundworm, is common in tropical countries like India. Owing to its variable clinical presentation and irregular larval output in stool, it often remains neglected and underdiagnosed. Signs and symptoms are largely dependent on the immune status of the infected individual.
View Article and Find Full Text PDFEur J Case Rep Intern Med
July 2021
WVU School of Medicine, Department of Infectious Diseases, Morgantown, WV, USA.
Unlabelled: Ciliocytophthoria is a phenomenon where degenerated cells in infections or malignancy can present as ciliated cells on microscopy and so may be confused with ciliated parasitic infection. We present an interesting case of recurrent shortness of breath, misdiagnosed as chronic obstructive pulmonary disease exacerbations leading to unnecessary exposure to antimicrobials and steroids. The case was diagnosed as hyper-infection syndrome.
View Article and Find Full Text PDFIDCases
June 2021
Department of General Medicine, All India Institute of Medical Sciences, Bhopal, India.
COVID-19 pandemic has posed formidable public health and clinical challenges to the entire humanity. A significant proportion of the COVID-19 patients have been provided immunosuppressive agents, particularly corticosteroids, as a part of management of moderate to severe COVID-19 disease. This has the drawback of development of strongyloides hyperinfection to disseminated infection in latent strongyloides infection patients.
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