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| http://dx.doi.org/10.1007/s11357-021-00425-y | DOI Listing |
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Polyphenol-Derived Microbiota Metabolites and Cardiovascular Health: A Concise Review of Human Studies.
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December 2024
Oklahoma Center for Geroscience and Healthy Brain Aging, University of Oklahoma Health Sciences, Oklahoma City, OK 73117, USA.
Polyphenols, plant-derived secondary metabolites, play crucial roles in plant stress responses, growth regulation, and environmental interactions. In humans, polyphenols are associated with various health benefits, particularly in cardiometabolic health. Despite growing evidence of polyphenols' health-promoting effects, their mechanisms remain poorly understood due to high interindividual variability in bioavailability and metabolism.
View Article and Find Full Text PDFWeight bias internalization statistically mediates the association between positive body image and intuitive eating: A cross-sectional study.
J Acad Nutr Diet
December 2024
Fort Lauderdale, Florida. At the time this work began, S. Rothenberg was a graduate student at Nova Southeastern University.
Background: Two facets of positive body image, body appreciation and functionality appreciation, are positively associated with an adaptive eating style known as intuitive eating. Little is known about the mechanisms underlying the association between positive body image and intuitive eating, although it is well established that weight bias internalization is associated with unfavorable views of the self and body and interferes with health behavior engagement.
Objective: The present cross-sectional study examined weight bias internalization as a statistical mediator of the association between positive body image (i.
Divergence in cannabis and alcohol use disorder prevalence trends from 2002 to 2019.
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Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, 5510 Nathan Shock Drive, Baltimore, MD 21224, USA. Electronic address:
Article Synopsis
- Daily cannabis use rose significantly by 94% from 2002 to 2019, but the prevalence of cannabis use disorder (CUD) among daily users decreased by nearly 48%.
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Apolipoprotein E Induces Lipid Accumulation Through Dgat2 That Is Prevented with Time-Restricted Feeding in .
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Department of Pathology, Division of Molecular and Cellular Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Apolipoprotein E (ApoE) is the leading genetic risk factor for late-onset Alzheimer's disease (AD), which is the leading cause of dementia worldwide. Most people have two ApoE-ε3 (ApoE3) alleles, while ApoE-ε2 (ApoE2) is protective from AD, and ApoE-ε4 (ApoE4) confers AD risk. How these alleles modulate AD risk is not clearly defined, and ApoE's role in lipid metabolism is also not fully known.
View Article and Find Full Text PDFMethyl-Beta-Cyclodextrin Restores Aberrant Bone Morphogenetic Protein 2-Signaling in Bone Marrow Stromal Cells Obtained from Aged C57BL/6 Mice.
J Dev Biol
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Department of Biological Sciences, University of Delaware, Newark, DE 19716, USA.
During aging, disruptions in various signaling pathways become more common. Some older patients will exhibit irregular bone morphogenetic protein (BMP) signaling, which can lead to osteoporosis (OP)-a debilitating bone disease resulting from an imbalance between osteoblasts and osteoclasts. In 2002, the Food and Drug Administration (FDA) approved recombinant human BMP-2 (rhBMP-2) for use in spinal fusion surgeries as it is required for bone formation.
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