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Zenker's Per-Oral Endoscopic Myotomy (Z-POEM): The Ideal First Line Therapy for Treatment of Zenker's Diverticulum.

J Thorac Cardiovasc Surg

December 2024

Section of Thoracic Surgery, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada; CancerCare Manitoba Research Institute, Winnipeg, Canada; Department of Physiology & Pathophysiology, University of Manitoba, Winnipeg, Canada; Department of Biomedical Engineering, University of Manitoba, Winnipeg, Canada. Electronic address:

Objective: Zenker's diverticulum is a mucosal herniation at the pharyngoesophageal junction. While open surgical myotomy is the conventional treatment, robust evidence on third-space flexible endoscopic myotomy is lacking. We assessed safety, effectiveness and patient-reported outcomes of per-oral endoscopic myotomy (Z-POEM) in the largest reported single-centre experience with this technique.

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The Endoscopic Management of Zenker's Diverticulum: A Comprehensive Review.

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Article Synopsis
  • Zenker's Diverticulum (ZD) is a common throat condition caused by a herniation of tissue, leading to difficulty swallowing (dysphagia) in most patients.
  • Traditional surgery for ZD has high technical challenges and can result in significant complications, prompting interest in less invasive endoscopic methods.
  • Newer endoscopic techniques like Zenker-POEM and Per Oral Endoscopic Septomyotomy offer alternative treatment options, which are discussed along with their pros, cons, and potential future developments.
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Cricopharyngeal achalasia (CPA), also known as cricopharyngeal bar, is a rare motor disorder affecting the upper oesophageal sphincter. This comprehensive literature review focuses on clinical aspects that can assist physicians in daily decision-making. The diagnosis of CPA is primarily based on symptoms of upper dysphagia and radiological identification of a posterior bar.

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Traditional septotomy or Z-POEM for Zenker's diverticulum.

Best Pract Res Clin Gastroenterol

August 2024

Department of Gastroenterology, Hepatology and Oncology, Medical Center for Postgraduate Education, Warsaw, Poland; Department of Gastroenterological Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland; Clinical Effectiveness Research Group, University of Oslo, Oslo, Norway; Department of General, Endocrine and Transplant Surgery, Medical University of Gdansk, Gdansk, Poland. Electronic address:

Article Synopsis
  • * It happens because of muscle spasms and issues with how the esophagus opens, leading to food getting stuck or coming back up.
  • * Doctors treat ZD using special methods that involve making small cuts in the muscle, with two modern techniques called FES and Z-POEM being less invasive and effective.
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