Purpose: A typical ion beam treatment facility has multiple treatment rooms and may treat with more than one ion species, thus requiring a significant quality assurance (QA) effort. The goal of this work was to perform daily QA using a single irradiation per ion species to obtain the beam dosimetry parameters of dose per monitor unit (D/MU), range, and spot position. The X-ray alignment system should also be checked and the entire procedure performed by therapists.
Methods: This goal was achieved by designing a jig for the Sun Nuclear Daily QA™ 3 device and combining it with specific brass boluses, a standard QA plan, and a cuboid polyethylene phantom for positioning/repositioning tests. The design of the plan used for each ion species delivery ensured that there was no interference between the tests of the various characteristics.
Results: The 1-year monitoring results showed the proposed daily QA procedure was reliable and able to reflect each of the specified QA items of the proton and carbon ion beams. To simplify the daily analysis, the tolerances for the D/MU, beam range, and spot position (±1.5%, ±0.3 mm, ±1.5 mm, respectively) are checked using only the detector readings without the need for additional data processing.
Conclusions: The proposed daily QA procedure was clinically implemented in our facility in April 2019 and has run smoothly for the first 2 years of operation. The total daily QA time for the four-room facility decreased from 1 to 1.5 h to 30 to 40 min and was achieved not by reducing QA tests but rather by implementing new technology and procedures permitting acquisition of multiple beam information.
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http://dx.doi.org/10.1002/mp.15151 | DOI Listing |
J Org Chem
January 2025
Antibiotics Research and Re-evaluation Key Laboratory of Sichuan Province, Sichuan Industrial Institute of Antibiotics, School of Pharmacy, Chengdu University, 2025 Chengluo Avenue, Chengdu 610016, P.R. China.
Herein, we report the first example that P(O)-H species including -phosphonates and -phosphine oxides could participate in a highly regioselective 1,4-addition to in situ generated 1-benzopyrylium ion from C3-substituted 2-chromene hemiketals, which provides a brand-new and effective approach for the synthesis of C4-phosphorylated 4-chromenes with diverse C3-functionality (ketone, ester, sulfonyl, aryl, and alkyl groups). In total, the reaction features the use of inexpensive Zn(ClO)·6HO as a catalyst, low catalyst loading (only 5 mol %), mild reaction conditions (60 °C, 10 min to 24 h), and broad substrate scope (46 examples) as well as good to high yields (>90% yield on average). More importantly, mechanistic experiments demonstrated the essential role of the C3-substituent on 2-chromene hemiketals in stabilizing the in situ generated 1-benzopyrylium ion and the regioselective 1,4-addition control.
View Article and Find Full Text PDFJ Vet Intern Med
January 2025
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA.
Background: Oxidative injury occurs in septic people, but the role of oxidative stress and antioxidants has rarely been evaluated in foals.
Objectives/hypothesis: To measure reactive oxygen species (ROS), biomarkers of oxidative injury, and antioxidants in neonatal foals. We hypothesized that ill foals would have higher blood concentrations of ROS and biomarkers of oxidative injury and lower concentrations of antioxidants compared to healthy foals.
Langmuir
January 2025
CSSC Nanjing Lvzhou Environmental Protection Co., Ltd, Nanjing 210039, China.
In this study, the MnFeO@CoS magnetic nanocomposite was prepared by a two-step hydrothermal method and used to catalyze the ozone oxidation degradation of methylene blue. It was characterized by XRD, EDS, SEM, FT-IR, and XPS. The results showed that the introduction of CoS made MnFeO grow uniformly on CoS nanosheets, which effectively prevented the agglomeration of MnFeO.
View Article and Find Full Text PDFChem Asian J
January 2025
Renmin University of China, Department of Chemistry, No 59 Zhongguancun St,, 100872, Beijing, CHINA.
The electroconversion of polyethylene terephthalate (PET) into C2 fine chemicals and hydrogen (H2) presents a promising solution for advancing the circular plastics economy. In this study, we report the electrooxidation of ethylene glycol (EG) to glycolic acid (GA) using a Pt-Ni(OH)2 catalyst, achieving a high Faraday efficiency (>90%) even at high current densities (250 mA cm-2 at 0.8 V vs.
View Article and Find Full Text PDFPhysiol Plant
January 2025
CAS Key Laboratory of Forest Ecology and Silviculture, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang, People's Republic of China.
Populus tree species are commonly used for creating shelter forests in vast areas of northern China, at least partially due to their fast growth. However, they are facing severe problems of decline and mortality caused by drought. In contrast, tree species native to water-limited environments usually have slow growth and are currently not commonly used in afforestation, while these species are gaining more attention in forestry for their greater resilience to drought.
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