Aim: The aim of the current study is to assess and evaluate the effectiveness of concentrated growth factors on wound healing after implant placement procedures.
Methodology: Twenty-four patients who underwent implant placement were included in the study and were divided into two groups (group 1 = non-CGF group; group 2 = CGF group). Conventional implant placement was done in both the groups followed by placement of CGF membrane and closure using 3-0 silk in the CGF group and only closure using 3-0 silk sutures in the control group. The patients were asked to report on the 3rd and 7th day respectively and the wound healing was assessed using an early wound healing index given by Lorenzo Marini.
Statistical Analysis: Shapiro-Wilk test was used to test the normality of the test, which was found to deviate from normal distribution and hence Mann-Whitney U test was employed to evaluate the statistical significance of the two independent samples.
Results: The mean ± SD was found to be 6.17 ± 2.04 for the control (group 1) and 5.67 ± 0.51 for CGF group (group 2) on the 3rd day. The mean and SD of control group and test group on the 7th day was 7 ± 1.55 and 9.33 ± 1.63, respectively. The difference between the groups on the 7th day was found to be statistically significant (P value < 0.05).
Conclusion: Concentrated growth factor application had positive effects on surgical wound healing after implant placement.
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http://dx.doi.org/10.1615/JLongTermEffMedImplants.2021036412 | DOI Listing |
Fracture-related infection (FRI) is a serious complication that occurs primarily in surgically treated fractures. FRIs occur when bacteria enter the site of bony injury and alter the healing inflammatory response within the bone. This can prevent bone regeneration and can lead to long-lasting complications such as chronic infection, pain, nonunion, and amputation.
View Article and Find Full Text PDFEur J Breast Health
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Department of General Surgery, Gülhane Training and Research Hospital, University of Health Sciences Turkey, Ankara, Turkey.
Pyoderma gangrenosum (PG) is a rare, chronic, neutrophilic dermatosis characterized by painful ulcers that are often misdiagnosed as wound infections. We report two cases of postsurgical PG following breast surgery: A 46-year-old woman with a non-healing ulcer after a breast biopsy and a 37-year-old woman with wound dehiscence after bilateral reduction mammoplasty. Both cases were initially managed with repeated debridements, antibiotics, and wound care without improvement.
View Article and Find Full Text PDFUrogynecology (Phila)
December 2024
University of Pittsburgh, Pittsburgh, PA.
Importance: Wound complications after obstetric anal sphincter injury (OASI) can amplify morbidity and affect quality of life.
Objective: The objective of this study was to evaluate for characteristics associated with wound complications after OASI.
Study Design: This was a retrospective cohort study of patients with an OASI who were evaluated in a postpartum pelvic floor healing clinic between November 1, 2020, and May 16, 2023.
J Adv Nurs
January 2025
School of Nursing, Beijing University of Chinese Medicine, Beijing, China.
Aims: To develop the core outcome set and identify unique outcomes for the three stages and five types of nursing interventions, respectively, in lactational mastitis.
Design: A mixed methods study.
Methods: A systematic literature search, four semi-structured interviews for key stakeholders, two rounds of Delphi surveys and two online consensus meetings were conducted.
J Cancer
January 2025
Department of Oral and Maxillofacial Surgery, School of Stomatology, Hebei Medical University, Hebei Technology Innovation Center of Oral Health, Key Laboratory of Stomatology and Clinical Research Centre for Oral Diseases, Hebei Province, Shijiazhuang, 050017, China.
HOXD13, a member of the homeobox gene family, plays a critical role in developmental processes and has been implicated in various malignancies, including pancreatic cancer and glioma. However, its role in oral squamous cell carcinoma (OSCC) remains poorly understood. This study aimed to elucidate the potential of HOXD13 as a diagnostic biomarker and therapeutic target for OSCC.
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