Brucella cardiac implantable electronic device infection: A single-center case series.

Background: Cardiac implantable electronic devices (CIEDs), including implantable cardiac defibrillators, pacemakers, and cardiac resynchronization therapy devices, are lifesaving. However, device infections can lead to morbidity and mortality. of this study was to describe the outcome of CIED infections treated at our center, and to identify risk factors for infection in patients with CIEDs. : Single-center study, Prince Sultan Military Medical City, Riyadh, KSA.

Methods: This case series included all -related CIED infections treated at a tertiary care center between 2009 and 2020. Data on patient demographics, clinical manifestations, predisposing factors, microbiology, treatment regimens, and outcomes were reviewed.

Results: Fifteen patients met the CIED infection criteria. The mean age was 62.2 years, and 80% were males. Common comorbidities included hypertension (73%), diabetes mellitus (67%), ischemic heart disease (47%), and chronic kidney disease (60%). The mean time to infection following the device implantation was 4.8 years (range: 5 months to 13 years). Fever was detected in 53% of patients, device site swelling in 47%, purulent discharge in 33%, and pain in 27%. The blood culture and serology results were positive in 73% and 80% of patients, respectively. All patients were treated with antibiotics, and the infected device was removed. Seven (46.6%) patients underwent reimplantation with a new device. One patient with dual and methicillin-sensitive infection died, and the other 14 patients recovered, with no recurrent infections reported to date.

Conclusion: should be considered in CIED infections, particularly in endemic areas. Proper treatment and device removal are essential for good outcomes.