Background: Recurrent implantation failure (RIF) is an obstacle in the process of assisted reproductive technology (ART). At present, there is limited research on its pathogenesis, diagnosis, and treatment methods.
Methods And Results: In this study, a series of analytical tools were used to analyze differences in miRNAs, mRNAs, and lncRNAs in the endometrium of patients in a RIF group and a control group. Then the competing endogenous RNA (ceRNA) network was built to describe the relationship between gene regulation in the endometrium of the RIF group. Based on the results of the logistic regression of co-expression miRNAs between serum and endometrial samples, we built a predictive model based on circulating miRNAs.
Conclusion: The stability and non-invasiveness of the circular miRNA prediction model provided a new method for diagnosis in RIF patients.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8344057 | PMC |
| http://dx.doi.org/10.3389/fgene.2021.712150 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Communicating hydrocephalus following stereotactic radiosurgery for periventricular meningiomas: illustrative cases.
J Neurosurg Case Lessons
January 2025
Victor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, University College London Hospitals, London, United Kingdom.
Background: Stereotactic radiosurgery (SRS) is a well-established option for the management of intracranial tumors, including meningiomas. Although valued for its low invasiveness and precision, it still carries a risk of complications. Communicating hydrocephalus is a serious, albeit rarely reported, complication of SRS.
View Article and Find Full Text PDFPipeline embolization device for aneurysm recurrence after stent-assisted coiling.
Neuroradiology
January 2025
Department of Neurosurgery, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Litang Road 168, Beijing, 102218, China.
Objective: Since the emergence of the Pipeline Embolization Device (PED), its off-label use has significantly improved the treatment effectiveness of complex intracranial aneurysms, including the treatment of recurrent aneurysms. Although PED is effective in this situation, there is still a lack of evidence-based medicine for its role in recurrent aneurysms after stent-assisted coiling. The aim of this study is to evaluate the safety and efficacy of PED treatment for recurrent aneurysms after stent-assisted coiling.
View Article and Find Full Text PDFStellate Ganglion Blockade as Rescue Therapy for Recurrent Torsades de Pointes and as a Bridge to Surgical Sympathectomy in a Pediatric Patient: A Case Report.
A A Pract
January 2025
From the Department of Anesthesia and Perioperative Medicine, University of California Los Angeles (UCLA) David Geffen School of Medicine, UCLA Health System, Los Angeles, California.
Management of refractory ventricular fibrillation (VF) in patients with implantable implantable cardioverter defibrillator (ICD) presents a therapeutic challenge. We present a case of pediatric refractory ventricular tachycardia (VT)/Torsade de Pointe managed effectively with bilateral stellate ganglion block (SGB) with a long-acting local anesthetic for 18 days as a bridge to more definitive surgical management.
View Article and Find Full Text PDFSpeech Enhancement for Cochlear Implant Recipients using Deep Complex Convolution Transformer with Frequency Transformation.
IEEE/ACM Trans Audio Speech Lang Process
February 2024
CRSS: Center for Robust Speech Systems; Cochlear Implant Processing Laboratory (CILab), Department of Electrical and Computer Engineering, University of Texas at Dallas, USA.
The presence of background noise or competing talkers is one of the main communication challenges for cochlear implant (CI) users in speech understanding in naturalistic spaces. These external factors distort the time-frequency (T-F) content including magnitude spectrum and phase of speech signals. While most existing speech enhancement (SE) solutions focus solely on enhancing the magnitude response, recent research highlights the importance of phase in perceptual speech quality.
View Article and Find Full Text PDFStatus Epilepticus Treated With Vagus Nerve Stimulation in an Adult With Cortical Dysplasia: A Case Report.
Cureus
December 2024
Epilepsy Clinic, National Institute of Neurology and Neurosurgery, Mexico City, MEX.
Status epilepticus (SE) is a neurological emergency characterized by prolonged seizures, with significant risks of neuronal injury and mortality. This case presents a 60-year-old man with drug-resistant epilepsy and a history of recurrent prolonged seizures. His seizures began in early childhood and persisted despite multiple anti-seizure medications.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!