The Effects of Ventilation and Filtration on Indoor PM in Office Buildings in Four Countries.

Fine particulate matter (PM) is an airborne pollutant associated with negative acute and chronic human health outcomes. Although the majority of PM research has focused on outdoor exposures, people spend the majority of their time indoors, where PM of outdoor origin can penetrate. In this work, we measured indoor PM continuously for one year in 37 urban commercial offices with mechanical or mixed-mode ventilation in China, India, the United Kingdom, and the United States. We found that indoor PM concentrations were generally higher when and where outdoor PM was elevated. In India and China, mean workday indoor PM levels exceeded the World Health Organization's 24-hour exposure guideline of 25 g/m about 17% and 27% of the time, respectively. Our statistical models found evidence that the operation of mechanical ventilation systems could mitigate the intrusion of outdoor PM: during standard work hours, a 10 g/m increase in outdoor PM was associated with 19.9% increase in the expected concentration of indoor PM (<0.0001), compared to a larger 23.4% increase during non-work hours (<0.0001). Finally, our models found that using filters with ratings of MERV 13-14 or MERV 15+ was associated with a 30.9% (95% CI: -55.0%, +6.2%) or 39.4% (95% CI: -62.0%, -3.4%) reduction of indoor PM, respectively, compared to filters with lower MERV 7-12 ratings. Our results demonstrate the potential efficacy of mechanical ventilation with efficient filtration as a public health strategy to protect workers from PM exposure, particularly where outdoor levels of PM are elevated.