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Associations Between Skeletal Alignment and Biomechanical Symmetry Before and After Transfemoral Bone-anchored Limb Implantation.
Clin Orthop Relat Res
December 2024
Department of Orthopedics, University of Colorado School of Medicine, Aurora, CO, USA.
Article Synopsis
- Patients with transfemoral amputation often face issues related to socket fit and overuse injuries due to uneven joint stress, which can be improved by using bone-anchored prosthetics that connect directly to the bone.
- This study investigates the relationship between the alignment of the femur and pelvis and how it impacts hip loading asymmetry during walking, both before and one year after receiving a bone-anchored limb implant.
- The analysis included 19 participants from a larger group who underwent the surgery, comparing their skeletal alignment and hip motion data collected at two different time points to determine the effects of the implantation on their mobility and joint loading.
Application of EMG feedback for hand prosthesis control in high-level amputation: a case study.
Sci Rep
December 2024
Department of Health Science and Technology, Aalborg University, Aalborg, Denmark.
EMG feedback improves force control of a myoelectric hand prosthesis by conveying the magnitude of the myoelectric signal back to the users via tactile stimulation. The present study aimed to test if this method can be used by a participant with a high-level amputation, and whose muscle used for prosthesis control (pectoralis major) was not intuitively related to hand function. Vibrotactile feedback was delivered to the participant's torso, while the control was tested using EMG from three different muscles.
View Article and Find Full Text PDFThyroid hormone receptor- and stage-dependent transcriptome changes affect the initial period of Xenopus tropicalis tail regeneration.
BMC Genomics
December 2024
Section On Molecular Morphogenesis, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA.
Background: Thyroid hormone (T3) has an inhibitory effect on tissue/organ regeneration. It is still elusive how T3 regulates this process. It is well established that the developmental effects of T3 are primarily mediated through transcriptional regulation by thyroid hormone receptors (TRs).
View Article and Find Full Text PDFFocused ion beam (FIB) prepared microtextured microneedle array capable of delivering drugs through punctured skin.
Sci Rep
December 2024
School of Mechanical Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan, 250353, China.
Microtextured microneedles are tiny needle-like structures with micron-scale microtextures, and the drugs stored in the microtextures can be released after entering the skin to achieve the effect of precise drug delivery. In this study, the skin substitution model of Ogden's hyperelastic model and the microneedle array and microtexture models with different geometrical parameters were selected to simulate and analyse the flow of the microtexture microneedle arrays penetrating the skin by the finite-element method, and the length of the microneedles was determined to be 200 μm, the width 160 μm, and the value of the gaps was determined to be 420 μm. A four-pronged cone was chosen as the shape of microneedles, and a rectangle was chosen as the shape of the drug-carrying microneedle.
View Article and Find Full Text PDFVascular Surgery in Japan: 2017 Annual Report by the Japanese Society for Vascular Surgery.
Ann Vasc Dis
December 2024
This is an annual report indicating the number and early clinical results of annual vascular treatment performed by vascular surgeons in Japan in 2017, as analyzed by Database Management Committee (DBC) members of the Japanese Society for Vascular Surgery (JSVS). To survey the current status of vascular treatments performed by vascular surgeons in Japan, the DBC members of the JSVS analyzed the vascular treatment data provided by the National Clinical Database, including the number of treatments and early results such as operative and hospital mortality. In total, 137,909 vascular treatments were registered by 1,076 institutions in 2017.
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