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Transcriptomic Profiles in Nasal Epithelium and Asthma Endotypes in Youth.
JAMA
January 2025
Division of Pediatric Pulmonary Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania.
Importance: T helper 2 (T2) cells and T helper 17 (T17) cells are CD4+ T cell subtypes involved in asthma. Characterizing asthma endotypes based on these cell types in diverse groups is important for developing effective therapies for youths with asthma.
Objective: To identify asthma endotypes in school-aged youths aged 6 to 20 years by examining the distribution and characteristics of transcriptomic profiles in nasal epithelium.
Residential Differences and Depression Among Older Adults With Dual Sensory Loss.
JAMA Otolaryngol Head Neck Surg
January 2025
Cochlear Center for Hearing and Public Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Importance: Investigating rural-urban and regional differences in the association between dual sensory loss (concurrent hearing and vision loss) and depression may highlight gaps in sensory loss research and health care services, and by socioeconomic status. Whether urbanicity and region may modify associations between sensory loss and depression is unknown.
Objective: To describe the rural-urban and regional differences in the association of dual sensory loss with depression among older adults.
Network analysis of intergenerational transmission of psychopathological symptom among adolescents: A cross-sectional study.
J Fam Psychol
January 2025
Department of Psychiatry, Renmin Hospital of Wuhan University.
The intergenerational transmission of psychopathology has been well documented, but limited studies have examined the link at the symptomatic level accounting for these associations. This study aimed to identify the central symptoms that bridge adolescents and parental psychopathological symptoms and the specific symptom pathways by using a novel network approach. From September to October 2021, a cross-sectional study was conducted in Wuhan, China.
View Article and Find Full Text PDFHistory of Multiple Allergies and Gradual Onset Running-Related Injuries in Distance Runners: SAFER XXXV.
Clin J Sport Med
January 2025
Sport, Exercise Medicine and Lifestyle Institute (SEMLI), Faculty of Healthy Sciences, University of Pretoria, Pretoria, South Africa.
Objective: To determine if any gradual onset running-related injury (GORRI) was associated with any allergies, multiple allergies (allergies to animals, plants, medication), and allergy medication use.
Design: Cross-sectional descriptive study.
Setting: Two Oceans Marathons (56 km, 21.
Characteristics of accountable care organizations' preferred skilled nursing facility networks.
Am J Manag Care
December 2024
Institute for Accountable Care, 2001 L St NW, Ste 500, Washington, DC 20036. Email:
Objectives: To describe the prevalence and characteristics of preferred skilled nursing facility (SNF) networks established by Medicare accountable care organizations (ACOs).
Study Design: Cross-sectional analysis of a 2019 Medicare ACO survey.
Methods: We analyzed surveys from 138 Medicare ACOs to assess preferred SNF network prevalence, characteristics, and challenges.
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