Retinal OCT Findings in Patients after COVID Infection.

Purpose: The aim of this study was to assess and compare the optic nerve, retina, and retinal vessel parameters in recovered COVID-19 patients and healthy patients by using optical coherence tomography angiography (OCT-a).

Methods: In all, 156 eyes of post-COVID-19 patients and 98 eyes of subjects from a control group were enrolled in our study. BCVA, intra ocular pressure (IOP) measurement, fundus examination, and OCT images, including macular cube, OCT-RNFL, and angio-OCT 6 × 6 mm examinations, were performed for both groups. The measurements were acquired using Swept Source OCT DRI OCT Triton. In the post-COVID-19 group, 762 OCT protocols were obtained. For statistical analysis, parameters from only one eye from each subject were taken.

Results: In the measured parameters, no significant differences were observed, i.e., central macular thickness ( = 0.249); RNFL ( = 0.104); FAZ ( = 0.63); and vessel density of superficial retinal vascular plexus in central ( = 0.799), superior ( = 0.767), inferior ( = 0.526), nasal ( = 0.402), and temporal ( = 0.582) quadrants. Furthermore, a slit-lamp examination did not reveal any COVID-19-related abnormalities.

Conclusion: OCT examination did not detect any significant changes in morphology or morphometry of the optic nerve, retina, or the retina vessels due to COVID-19.