Impact of Dietary Patterns on Infection and the Modulation of Microbiota to Counteract Its Effect. A Narrative Review.

Pathogens

Center of Biomedical Research, Institute of Nutrition and Food Technology "José Mataix", University of Granada, Avda. del Conocimiento s/n., Armilla, 18016 Granada, Spain.

Published: July 2021

is a Gram-negative bacterium that colonizes the stomach and can induce gastric disease and intra-gastric lesions, including chronic gastritis, peptic ulcers, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. This bacterium is responsible for long-term complications of gastric disease. The conjunction of host genetics, immune response, bacterial virulence expression, diet, micronutrient availability, and microbiome structure influence the disease outcomes related to chronic infection. In this regard, the consumption of unhealthy and unbalanced diets can induce microbial dysbiosis, which infection with may contribute to. However, to date, clinical trials have reported controversial results and current knowledge in this field is inconclusive. Here, we review preclinical studies concerning the changes produced in the microbiota that may be related to infection, as well as the involvement of diet. We summarize and discuss the last approaches based on the modulation of the microbiota to improve the negative impact of infection and their potential translation from bench to bedside.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308520PMC
http://dx.doi.org/10.3390/pathogens10070875DOI Listing

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