Thorough knowledge of the dynamics of spp. infestation could help to control the spread of schistosomiasis. This study describes the spatio-temporal dynamics of and infestation by the group of blood flukes in Niakhar, Senegal. Molecular identification of the group was performed by real-time PCR, targeting the Dra 1 gene in 810 samples of spp. collected during the schistosomiasis transmission season in 2013. In addition to Dra 1 PCR, a rapid diagnostic-PCR was performed on a sub-group of 43 snails to discriminate , , and Out of 810 snails, 236 (29.1%) were positive for Dra 1 based on the PCR, including 96.2% and 3.8% of and respectively. Among the sub-group, 16 samples were confirmed to be while one was identified as a mixture of and . Snails infestations were detected in all villages sampled and infestation rates ranged from 15.38% to 42.11%. The prevalence of infestation was higher in the north (33.47%) compared to the south (25.74%). Snail populations infestations appear early in the rainy season, with a peak in the middle of the season, and then a decline towards the end of the rainy season. Molecular techniques showed, for the first time, the presence of in the spp. population of Niakhar. The heterogeneity of snail infestations at the village level must be taken into account in mass treatment strategies. Further studies should help to improve the characterizations of the schistosome population.
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http://dx.doi.org/10.3390/pathogens10070860 | DOI Listing |
iScience
January 2025
Program in Public Health, College of Health Sciences, University of California, Irvine, Irvine, CA 92697, USA.
Freshwater snails are obligate intermediate hosts for the transmission of schistosomiasis, one of the world's most devastating parasitic diseases. To decipher the mechanisms underlying snail resistance to schistosomes, recombinant inbred lines (RILs) were developed from two well-defined homozygous lines (iM line and iBS90) of the snail . Whole-genome sequencing (WGS) was used to scan the genomes of 46 individual RIL snails, representing 46 RILs, half of which were resistant or susceptible to .
View Article and Find Full Text PDFActa Parasitol
January 2025
World Health Organization Regional Office for Southeast Asia, New Delhi, India.
Purpose: A comprehensive survey was conducted to assess the prevalence of Schistosoma japonicum infection in humans, water buffaloes, and snails in the two endemic municipalities of Talibon and Trinidad in Bohol, Philippines, which are nearing elimination.
Methods And Results: Human stool and blood samples were collected from barangays with snail breeding sites, and results showed higher positivity rates using the rSjTPx-1-ELISA compared to the Kato-Katz technique. Human stool examination for showed a 0.
PLoS Negl Trop Dis
January 2025
School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.
Lake Victoria is a well-known hot spot for intestinal schistosomiasis, caused by infection with the trematode Schistosoma mansoni. The snail intermediate hosts of this parasite are Biomphalaria snails, with Biomphalaria choanomphala being the predominant intermediate host within Lake Victoria. The prevalence of S.
View Article and Find Full Text PDFPeerJ
December 2024
Grupo de Salud Animal, Instituto Nacional de Tecnología Agropecuaria (INTA), San Carlos de Bariloche, Río Negro, Argentina.
Background: The trematode parasite (liver fluke) can infect livestock, wild mammals, and humans, generating serious economic losses worldwide. Aquatic or amphibious snails of the Lymnaeidae family are the intermediate host of this parasite. Both snail population dynamics and parasite development are closely associated with temperature, although most field studies have recorded air temperature rather than water temperature.
View Article and Find Full Text PDFParasite
December 2024
Pacific Biosciences Research Center, University of Hawaii at Manoa, Honolulu, Hawaii, USA.
Understanding the factors driving infection prevalence among host species is crucial for effective disease mitigation. Angiostrongylus cantonensis, the rat lungworm, causes neuroangiostrongyliasis and serves as an excellent model for studying infection dynamics across hosts. This study investigates the relative impact of encounter rates on A.
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