AI Article Synopsis
- Scars can significantly impact a person's quality of life, and this study focuses on the effectiveness of autologous nanofat injection as a treatment.
- The study involved 30 patients with various types of scars, who received the injection and were evaluated after 6 months using a clinical scale and histopathological analysis.
- Results showed significant improvements in scar characteristics, such as height and pliability, along with observable changes in skin structure at the cellular level, indicating that nanofat injections are a promising option for scar treatment.
Article Abstract
Background: Scars are the unfortunate outcome of most injuries and some diseases. Its psychological impact on patients can deeply affect their quality of life.
Aim: The aim of this study was to evaluate the efficacy of autologous nanofat injection in improving the aesthetic outcome of scars, combined with histopathological correlation of the response.
Patients And Methods: Thirty patients with scars of different etiologies undergone one session of nanofat injection and evaluation was done 6 months after the session. Efficacy of treatment was assessed clinically using Vancouver scar scale by two independent blinded dermatologists and histopathologically using image analysis system.
Results: The age of enrolled patients ranged from 18 to 40 years old. There was a statistically significant improvement on the total Vancouver scar scale regarding the height and pliability of the scars. Pathological evaluation showed an increase in epidermal thickness, increased number and density of collagen and elastic fibers along with neovascularization.
Conclusion: Evidenced by clinical and pathological improvement, autologous nanofat injection is an effective strategy for treating scars of different etiologies.
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| http://dx.doi.org/10.1111/jocd.14363 | DOI Listing |
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