AI Article Synopsis
- The research investigated the presence and characteristics of "starry sky" liver pattern in owl monkeys, which reflects multiple bright spots visible in liver ultrasounds.
- Out of 37 studied monkeys, 59.4% displayed this pattern, and biopsies revealed various liver issues, including steatosis and granulomatous hepatitis.
- The study concluded that the combination of different liver lesions, including peliosis hepatis and granulomatous hepatitis, contributes to the starry sky appearance, suggesting a need for careful clinical monitoring of affected monkeys.
Article Abstract
Background: The "starry sky" (SK) liver is ultrasonographic pattern characterized by multiple hyperechogenic foci in hepatic parenchyma. The study aimed to characterize the microscopic hepatic lesions in captive owl monkeys with SK liver.
Methods: Thirty-seven clinically healthy owl monkeys had their liver scanned and 18 of them had liver biopsy. Animals with SK and peliosis hepatis (PH) were subjected to immunohistochemical and molecular screening for Bartonella spp.
Results: SK liver occurred in 59.4% (22/37) of the owl monkeys. Biopsied animals showed steatosis, hydropic degeneration, hemosiderosis, PH, and multifocal granulomatous hepatitis. Two monkeys had SK, granulomatous hepatitis, and PH which were negative for Bartonella spp.
Conclusions: PH and granulomatous hepatitis associated with hepatocellular degenerative lesions may present as hyperechoic nodular liver lesions consisted of SK liver; therefore, concomitant occurrence of two lesions or more contributed to the hepatic SK pattern among owl monkeys and such cases might be clinically monitored.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/jmp.12535 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!