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Influence of COVID-19 on Patients with Esophageal Varices under Prophylactic Endoscopic Band Ligation Therapy.
GE Port J Gastroenterol
June 2024
Gastroenterology and Hepatology Department, Hospital de Santa Maria, Lisbon, Portugal.
Background And Objectives: Endoscopic band ligation (EBL) plays a critical role in patients with clinically significant portal hypertension, as variceal eradication (VE) is essential to prevent further variceal upper gastrointestinal bleeding (GI). The emergence of COVID-19 has led to a dramatic reduction in endoscopic activity. Our study aimed to evaluate the effect of COVID-19 on VE, GI, and 6-month mortality of patients treated with prophylactic EBL therapy.
View Article and Find Full Text PDFHistopathology of Eosinophilic Esophagitis.
Immunol Allergy Clin North Am
May 2024
Department of Pathology, Ward Building Ward 4-115, Northwestern University Feinberg School of Medicine, 303 East Chicago Avenue, Chicago, IL. 60611, USA.
Article Synopsis
- - Microscopic examination of esophageal biopsies is crucial for diagnosing eosinophilic esophagitis (EoE), focusing on eosinophil inflammation but also considering other abnormalities.
- - Pathology reports should include both peak eosinophil counts and other features before and after therapy.
- - Unlike esophageal strictures, the pathological changes found in EoE biopsies can be reversed with appropriate treatment.
Endoscopic Glue Injection Versus Endoscopic Human Thrombin Injection for Bleeding Gastric Varices-A Randomized Controlled Trial.
J Clin Gastroenterol
September 2024
Department of Gastroenterology, SMS Medical College and Hospital, Jaipur, Rajasthan, India.
Background: Acute gastric variceal bleeding (AGVB) is a potentially fatal consequence of portal hypertension, accounting for 10% to 30% of all variceal bleeding. Although endoscopic cyanoacrylate glue injection is a common treatment for acute hemostasis, it has been linked to significant side effects. In the treatment of AGVB, there is limited evidence of the efficacy and relative safety of endoscopic human thrombin injection over glue injection.
View Article and Find Full Text PDFUnmet needs in Barret's esophagus diagnosis and treatment: a narrative review.
Transl Gastroenterol Hepatol
June 2023
Department of Gastroenterology, NYU-Langone-Long Island, Mineola, NY, USA.
Background And Objective: This narrative review discusses Barrett's esophagus management in the context of perceived deficiencies or controversies. Barrett's adenocarcinoma incidence has not clearly been impacted by Barrett's screening and surveillance.
Methods: The following report was derived from articles using PubMed and Google searches.
PET Imaging and Rate of Pathologic Complete Response in Esophageal Squamous Cell Carcinoma.
Ann Surg Oncol
February 2022
Division of Surgical Oncology, Department of Surgery, Carolinas Medical Center, Levine Cancer Institute, Atrium Health, Charlotte, NC, USA.
Background: For locally advanced esophageal squamous cell carcinoma (ESCC), chemoradiation (ChemoRT) followed by surgery offers the best chance of cure, with a 35-50% pathologic complete response (pCR) rate. Given the morbidity of esophagectomy and the possibility of pCR with ChemoRT, a 'watch and wait' strategy has been proposed, particularly for squamous cell carcinoma. The ability to accurately predict which patients will have pCR from ChemoRT is critical in treatment decision making.
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