Trends in the Utilization and Dose of Gabapentinoids in Combination With Opioids in an Injured Worker Population Between 2008 and 2018.

Robert A Lavin Che Liu Larry Yuspeh Nimisha Kalia Nina Leung Nicholas F Tsourmas Leila Williams Dan L Hunt Edward J Bernacki Xuguang Grant Tao

J Occup Environ Med

Department of Neurology, University of Maryland School of Medicine, Baltimore, Maryland (Dr Lavin); Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland (Dr Lavin, Mr Yuspeh, Dr Kalia, Dr Leung, Dr Tsourmas, Dr Bernacki, and Dr Tao); Occupational and Environmental Medicine Residency Program, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (Dr Liu); Strategy, Enterprise Risk, and Research, Louisiana Workers' Compensation Corporation, Baton Rouge, Louisiana (Mr Yuspeh); The General Electric Company, Cincinnati, Ohio (Dr Kalia); Texas Mutual: Workers' Compensation Insurance, Austin, Texas (Dr Leung, Dr Tsourmas, and Dr Williams); Corporate Administration Office, AF Group, Lansing, Michigan (Dr Hunt).

Published: October 2021

Objective: To determine long term (11 year) trends in gabapentin and pregabalin prescribing among workers' compensation claimants at various opioid dose combinations (low, medium, high, and very high) in Louisiana.

Method: A longitudinal study of 18,737 claimants who filled any prescriptions between 2008 and 2018.

Results: The proportion of claimants prescribed opioids alone at all dose levels decreased dramatically. The proportion claimants prescribed the combination of low dose opioids and low dose gabapentinoids increased (7.7% to 10.9%). Prescribing higher daily doses of gabapentinoids was associated with higher daily doses of opioids. Gabapentinoid prescribing was associated with continued prescribing of medium and high dose opioids as claims matured.

Conclusions: Overall opioid prescribing decreased over time, while prescribing low dose opioids with gabapentinoids, increased.

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http://dx.doi.org/10.1097/JOM.0000000000002344	DOI Listing

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