In a critical review of 29 analytical papers from the 1985 Australian and New Zealand Journal of Psychiatry and the American Journal of Psychiatry, examples of 10 methodological errors were found. Twenty-three papers contained at least one error. The commonest error in design was the failure to assess outcome independently of knowledge of the subjects' groups. The most frequent error in analysis was the failure to control for the increased type I error rate when multiple comparisons were made. The high frequency of statistical errors in published articles indicates a need for research methodology to be included in postgraduate psychiatry training. The limitations of statistical designs highlight the importance of alternative investigative models in psychiatric research.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1080/00048678709160933 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Points regarding neuroscience-based nomenclature: evaluating its impact on psychiatric residency training.
Int Clin Psychopharmacol
March 2025
Department of Neuroscience, University Psychiatric Center, Catholic University of Leuven, Psychiatry Research Group, Leuven, Belgium.
This study evaluates the impact of neuroscience-based nomenclature (NbN) training on psychiatric residents in Flanders, Belgium. Addressing Zemach et al.'s findings on NbN's potential, we investigated its application in clinical practice.
View Article and Find Full Text PDFChallenges for switching central nervous system and psychiatric medication products: A review of the literature.
J Psychopharmacol
January 2025
Department of Psychiatry, McGill University, Montreal, QC, Canada.
Background: Switching between versions of medication products happens commonly despite challenges in achieving bioequivalence and therapeutic equivalence. Central nervous system and psychiatric drugs, especially those that are technically demanding to manufacture and have complex pharmacokinetic properties, such as long-acting injectables (LAIs), pose particular challenges to bioequivalence and safe and efficacious drug switching.
Aims: To assess whether drugs deemed "bioequivalent" are truly interchangeable in drug switching.
Investigating the Association Between Heavy Metals and Attention Deficit Hyperactivity Disorder in Children: An Exploratory Study.
J Atten Disord
January 2025
Nutrition and Mental Health Research Group (NUTRISAM), Universitat Rovira i Virgili, Tarragona, Spain.
Exposure to heavy metals has been associated with affecting children's neurodevelopment, particularly increasing the risk of developing attention-deficit hyperactivity disorder (ADHD). The current exploratory study aims to investigate potential associations between presence of 15 different heavy metals in urine and ADHD. A total of 190 urine samples of participants from clinical and non-clinical population (non-ADHD = 66; ADHD = 124) aged between 6 and 15 years from Barcelona and Tarragona (Spain) were analysed.
View Article and Find Full Text PDFAssociations of polygenic scores and developmental trajectories of externalizing behaviors.
Dev Psychopathol
January 2025
Department of Psychology, University of Wisconsin-Madison, Madison, WI, USA.
Polygenic scores (PGSs) have garnered increasing attention in the clinical sciences due to their robust prediction signals for psychopathology, including externalizing (EXT) behaviors. However, studies leveraging PGSs have rarely accounted for the phenotypic and developmental heterogeneity in EXT outcomes. We used the National Longitudinal Study of Adolescent to Adult Health (analytic = 4,416), spanning ages 13 to 41, to examine associations between EXT PGSs and trajectories of antisocial behaviors (ASB) and substance use behaviors (SUB) identified via growth mixture modeling.
View Article and Find Full Text PDFInterparental mutually responsive orientation during pregnancy impacts toddler socioemotional development by promoting parent-infant relational dynamics.
Dev Psychopathol
January 2025
Department of Psychology, University of Nebraska-Lincoln, Lincoln, NE, USA.
Child socioemotional difficulties emerge as early as infancy, increase over time, and place children at risk for future internalizing and externalizing symptoms. The aim of the present study was to investigate pathways that originate within the interparental relationship during pregnancy and unfold during infancy that mitigate risk for toddler socioemotional difficulties and to examine the differential effects of these pathways for children with varying degrees of temperamental fearfulness. Specifically, we examined whether dyadic (MRO; i.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!