Lutetium-177 (Lu)-based post-therapeutic imaging allows visualization of treated lesions andabsorbed dose measurement. There is an increasing number of cadmium-zinc-telluride (CZT) gamma-cameras in nuclear medicine departments but until now these devices were not adapted to the medium-energy emission of Lu photons. We present here in the first reported images acquired with a new collimator designed for CZT gamma-camera compared to a conventional sodium iodide (NaI) (Tl) gamma-camera. Post-therapeutic Lu-DOTATATE imaging on a CZT device with a medium energy high resolution (MEHRS)-collimator are promising and support the widespread of both Lu-based peptide-receptor radionuclide therapy (PRRT) and CZT gamma-cameras.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1967/s002449912361 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Recent Progress in Myocardial Perfusion Imaging Techniques.
Nucl Med Mol Imaging
December 2024
Department of Nuclear Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
Article Synopsis
- Nuclear cardiology has advanced rapidly, particularly in myocardial perfusion imaging (MPI) since the 1970s, which is vital for assessing and managing coronary artery disease.
- Recent innovations include the development of gamma cameras with cadmium zinc telluride (CZT) systems and enhancements in software, as well as ongoing studies into new radiopharmaceuticals for positron emission tomography (PET)-MPI.
- Despite these advancements, challenges like high equipment and examination costs, along with limited accessibility, pose significant barriers to the practical use of these technologies in nuclear medicine.
Verification of reprojected planar images generated from a ring-configured cadmium zinc telluride gamma camera in scintigraphy for diagnosing transthyretin cardiac amyloidosis.
Eur Heart J Imaging Methods Pract
January 2024
Radiation Physics, Department of Haematology, Oncology and Radiation Physicis, Skåne University Hospital, 221 85 Lund, Sweden.
Article Synopsis
- The study investigates the use of reprojected planar images from newer ring-configured CZT gamma cameras as a substitute for traditional planar scintigraphy in diagnosing ATTR cardiac amyloidosis using [Tc]Tc-DPD.
- Both imaging methods were tested on 30 patients, comparing results from conventional and CZT gamma cameras, focusing on image quality and consistency in scoring.
- Findings indicate that reprojected images can effectively assess ATTR amyloidosis, with strong agreement in scoring and measurement ratios, although a slight decrease in image quality was noted.
Performance evaluation of the 3D-ring cadmium-zinc-telluride (CZT) StarGuide system according to the NEMA NU 1-2018 standard.
EJNMMI Phys
July 2024
Unit of Nuclear Medicine, Department of Medicine (DIMED), University Hospital of Padova, Padua, Italy.
Background: The application of semi-conductor detectors such as cadmium-zinc-telluride (CZT) in nuclear medicine improves extrinsic energy resolution and count sensitivity due to the direct conversion of gamma photons into electric signals. A 3D-ring pixelated CZT system named StarGuide was recently developed and implemented by GE HealthCare for SPECT acquisition. The system consists of 12 detector columns with seven modules of 16 × 16 CZT pixelated crystals, each with an integrated parallel-hole tungsten collimator.
View Article and Find Full Text PDFClinical Impact of Assessment of Myocardial Flow Reserve in Identifying the Cause of Chest Discomfort.
Arq Bras Cardiol
July 2024
Instituto Nacional de Cardiologia, Rio de Janeiro, RJ - Brasil.
Background: Gamma cameras with cadmium-zinc telluride (CZT) detectors allowed the quantification of myocardial flow reserve (MBF), which can increase the accuracy of myocardial perfusion scintigraphy (MPS) to detect the cause of chest discomfort.
Objective: To assess the clinical impact of MBF to detect the cause of chest discomfort.
Methods: 171 patients with chest discomfort who underwent coronary angiography or coronary CT angiography also underwent MPS and MBF in a time interval of <30 days.
A practical method for measuring planar spatial resolution with scatter on a CZT gamma camera.
EJNMMI Phys
July 2024
Service de Physique Médicale et Radioprotection, Groupement Hospitalier Est, Hospices Civils de Lyon, Bâtiment Pinel, 52 Bd Pinel, Lyon, Bron, 69677, France.
Purpose: This study proposes a practical method for evaluating 2D spatial resolution with scatter on a CZT planar detector gamma camera, which is simpler and faster than the NEMA method. It is used to characterize the influence of distance on spatial resolution FWHM on a CZT camera equipped with a WEHR collimator.
Methods: The practical method uses linear sources tilted with respect to the detector axes.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!