Association between obesity and chronic obstructive pulmonary disease in Moroccan adults: Evidence from the BOLD study.

Objective: The Moroccan cross-sectional study aimed to investigate obesity in association to chronic obstructive pulmonary disease in Fez city.

Methods: A cross-sectional survey was carried out in Moroccan adults. Anthropometric and spirometry measurements were performed using standardized guidelines.

Results: Among the 744 participants, 53.9% of were women, with a mean age of 55.27 years (SD = 10.29). Nearly all women declared themselves to be never smokers, while 21% of men were current smokers. Overall, chronic obstructive pulmonary disease prevalence decreased with body mass index ( = 0.01) and waist circumference ( < 0.001). The same trends were also observed in women. The adjusted regression analysis showed a significant independent association between chronic obstructive pulmonary disease and decreasing overweight (OR: 0.66; CI (0.40-0.98)), obesity (OR: 0.66 CI: (0.36-0.89)), and a decreasing waist circumference-abdominal obesity (OR: 0.58 CI: (0.34-0.99)) in the whole population. The same association remains significant in women for overweight (OR: 0.18 CI: (0.06-0.54)) and for waist circumference-abdominal obesity (OR: 0.40 CI: (0.19-0.85)). All these associations disappeared for men.

Conclusion: Chronic obstructive pulmonary disease decreases with the increase in body mass index and waist circumference. The effect of waist circumference on the chronic obstructive pulmonary disease was greater among women, regardless of the tobacco factor. A multicenter study would help to confirm the accuracy of these findings in a larger sample of the Moroccan population. Developed lifestyle programs in patients with chronic obstructive pulmonary disease should be considered.