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Impact of delayed adoption of novel atrial fibrillation treatments.
Am J Manag Care
December 2024
Center for Healthcare Economics and Policy, FTI Consulting, 350 S Grande Ave, Los Angeles, CA 90071. Email:
Objective: To examine the relationship between adoption of direct oral anticoagulants (DOACs) and health and cost outcomes for patients with nonvalvular atrial fibrillation.
Study Design: Real-world cohort study.
Methods: US adults who newly initiated treatment for nonvalvular atrial fibrillation were identified from claims data.
Association between childhood adversity and use of the health, social, and justice systems in Denmark (DANLIFE): a nationwide cohort study.
Lancet Public Health
January 2025
Copenhagen Health Complexity Center, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.
Background: Childhood adversities can negatively affect health and social outcomes. We aimed to assess the association between adversity in childhood and use of public services in early adulthood across three systems: health, social welfare, and justice.
Methods: We used Danish nationwide registry data on individuals born between 1980 and 1991 and followed up between 1998 and 2021.
Patterns in California Ambulance Patient Offload Times by Local Emergency Medical Services Agency.
JAMA Netw Open
December 2024
Department of Emergency Medicine, University of California, San Francisco.
Importance: Ambulance offload delays are a timely and crucial issue with implications for patients, emergency medical services (EMS) agencies, hospitals, and communities. Published data on recent patterns in ambulance patient offload times (APOTs) are sparse.
Objective: To examine patterns in APOT by California local EMS agency and variation between and within local agencies.
Temporal Trends in Mortality Related to Stroke and Atrial Fibrillation in the United States: A 21-Year Retrospective Analysis of CDC-WONDER Database.
Clin Cardiol
December 2024
Keele Cardiovascular Research Group, Keele University, Stoke on Trent, UK.
Aims: Atrial Fibrillation (AF) is one of the most strongly associated risk factors for stroke. Our study aims to analyze changes in mortality from 1999 to 2020 in patients with AF and stroke.
Methods: Using the Centre for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC-WONDER), we retrospectively analyzed annual age-adjusted mortality rates (AAMR) per million from 1999 to 2020 in stroke patients with AF.
Rising Mortality of Intrahepatic Cholangiocarcinoma Among Older Adults in the United States: An Analysis of Demographic and Regional Trends.
Liver Int
January 2025
Department of Medicine, Arnot Ogden Medical Center, Elmira, New York, USA.
Introduction: Intrahepatic cholangiocarcinoma (ICC) is the second most frequent primary liver malignancy after hepatocellular carcinoma. Contemporary mortality trends due to ICC are largely unknown. We aim to examine the temporal trends of ICC-related deaths among older adults in the United States from 1999 to 2022.
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