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Ignoring Gender-Based Immunometabolic Reprograming, a Risky Business in Immune-Based Precision Medicine.
Front Biosci (Landmark Ed)
January 2025
Department of Surgery, Laboratory of Tumor Immunology and Immunotherapy, Morehouse School of Medicine, Atlanta, GA 30310, USA.
Immunology advances have increased our understanding of autoimmune, auto-inflammatory, immunodeficiency, infectious, and other immune-mediated inflammatory diseases (IMIDs). Furthermore, evidence is growing for the immune involvement in aging, metabolic and neurodegenerative diseases, and different cancers. However, further research has indicated sex/gender-based immune differences, which further increase higher incidences of various autoimmune diseases (AIDs), such as systemic lupus erythematosus (SLE), myasthenia gravis, and rheumatoid arthritis (RA) in females.
View Article and Find Full Text PDFHow climate change is shaping young people's health: a participatory, youth co-led study from Bangladesh, Guatemala and Nigeria.
BMJ Glob Health
January 2025
Population Council, Nairobi, Kenya.
Introduction: Climate change is shaping adolescent and young people's (AYP) transitions to adulthood with significant and often compounding effects on their physical and mental health. The climate crisis is an intergenerational inequity, with the current generation of young people exposed to more climate events over their lifetime than any previous one. Despite this injustice, research and policy to date lacks AYP's perspectives and active engagement.
View Article and Find Full Text PDFAreas for action to promote positive forms of masculinities in preventing violence against women: a concept mapping study in Spain.
Int J Equity Health
January 2025
Department of Community Nursing, Preventive Medicine and Public Health and History of Science, University of Alicante, Alicante, Spain.
Background: Violence against women (VAW) perpetrated by men is a public health problem of significant magnitude that negatively affects the whole society. Unequal gender relations produce differentiated positions in the social structure; gender roles that position men and women differently are defined and which are at the root of VAW. Framed within the European PositivMasc project, the aim of this study was to identify the areas for action to promote positive masculinities in preventing VAW in Spain, based on community stakeholders' perceptions on their importance and applicability.
View Article and Find Full Text PDFBeyond COVID-19, the case for collecting, analysing and using sex-disaggregated data and gendered data to inform outbreak response: a scoping review.
BMJ Glob Health
January 2025
PUBLIC HEALTH EMERGENCIES, UNICEF, Kinshasa, Congo (the Democratic Republic of the).
Introduction: Understanding sex and gender differences during outbreaks is critical to delivering an effective response. Although recommendations and minimum requirements exist, the incorporation of sex-disaggregated data and gender analysis into outbreak analytics and response for informed decision-making remains infrequent. A scoping review was conducted to provide an overview of the extent of sex-disaggregated data and gender analysis in outbreak response within low- and middle-income countries (LMICs).
View Article and Find Full Text PDFExploring parenthood intentions and perceptions of infertility and assisted reproductive technology among 2SLGBTQIA + young adults in Ontario, Canada: a mixed methods study.
J Health Popul Nutr
January 2025
Faculty of Health Sciences, Interdisciplinary School of Health Sciences, University of Ottawa, 25 Université Priv, Ottawa, K1N 6N5, Canada.
Background: As Generation Z two-spirit, lesbian, gay, bisexual, transgender/trans, queer, intersex, asexual and others who identify as part of sexual and gender diverse communities (2SLGBTQIA +) enter adulthood, contemplation of family creation may be challenged by biological and/or social infertility. Despite some advances in societal acceptance of gender and sexual minorities, family planning and reproductive healthcare remain heteronormative. To explore reproductive decision-making and how future families are conceptualized across genders, we evaluated perceptions of Ontario, Canada non-parenting, 2SLGBTQIA + emerging adults.
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