Objective: To explore the association between measures of obesity and measures of trip-induced fall risk among community-dwelling older adults.
Design: Case-control.
Setting: Gait laboratory.
Participants: Voluntary sample of 55 community-dwelling older adults (aged ≥65y; N=55) with body mass index (BMI) of 18.84-44.68 kg/m.
Interventions: Not applicable.
Main Outcome Measures: Measures of obesity included 6 anthropometry-based measures (BMI; thigh, hip and waist circumferences; ratio of waist-to-hip circumference; index of central obesity) and 4 dual-energy x-ray absorptiometry-based measures (percentage trunk, leg, and total fat; fat mass index). Measures of risk of tripping during overground walking included median and interquartile range of toe clearance and area under the swing phase toe trajectory. Measures of trip recovery after a laboratory-induced trip included trunk angle and angular velocity at ground contact of the first recovery step, anteroposterior distance from stepping foot to center of mass at the same instant, and step time of the first recovery step.
Results: Risk of tripping was associated with waist-to-hip ratio and thigh circumference. After grouping participants by waist-to-hip ratio, those with high ratios (≥0.9 cm for men and ≥0.85 cm for women) exhibited significantly greater variability in toe clearance. Trip recovery was associated with hip circumference, thigh circumference, fat mass index, and total fat. After grouping participants by fat mass index, those with high indices (>9 kg/m for men and >13 kg/m for women) exhibited less favorable trunk kinematics after a laboratory-induced trip (Cohen d=0.84).
Conclusions: Waist-to-hip ratio and fat mass index may more closely relate to trip-induced fall risk than BMI among community-dwelling older adults.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648946 | PMC |
http://dx.doi.org/10.1016/j.apmr.2021.06.013 | DOI Listing |
Int J Gynaecol Obstet
January 2025
Department of Radiology, Affiliated Hospital 2 of Nantong University, Nantong City, Jiangsu Province, China.
Objective: To develop and validate an individualized nomogram for predicting adnexal torsion in women with abdominal pain and an adnexal mass based on preoperative non-contrast computed tomography (CT) findings.
Methods: This retrospective study included 200 women with surgically resected ovarian lesions who underwent preoperative non-contrast CT for abdominal pain from January 2017 to September 2023 in seven hospitals. The 200 patients were randomly divided into a development group (140 cases) and a validation group (60 cases).
Am J Reprod Immunol
January 2025
Laboratory of Molecular Genetics and Experimentation in Animal Reproduction, University of Western São Paulo (Unoeste), Presidente Prudente, São Paulo, Brazil.
Problem: A high-fat diet (HFD) predisposes animals to glucose intolerance, dyslipidemia and testicular oxidative stress, and impairs sperm production in rats. Quercetin is a flavonoid with antioxidant, anti-inflammatory, and lipolytic actions and is a potential supplement to combat the oxidative stress caused by HFD and its harmful effects on reproduction. This study evaluated the effects of quercetin supplementation at doses of 10 and 20 mg/day on reproductive parameters and testicular oxidative stress in Wistar rats fed a diet rich in pork fat and fructose.
View Article and Find Full Text PDFPediatr Obes
January 2025
Growth, Exercise, Nutrition and Development (GENUD) Research Group, Instituto Agroalimentario de Aragón (IA2), University of Zaragoza, Zaragoza, Spain.
Background: Although the genetic interplay with the environment has a major impact on obesity development, little is known on whether breastfeeding could modulate the genetic predisposition to obesity.
Objectives: To investigate whether breastfeeding attenuates the effect of an obesity genetic risk score (GRS) on adiposity in European adolescents.
Methods: Totally 751 adolescents from the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) cross-sectional study were included, divided according to breastfeeding status into never breastfed, 1-3 months and ≥4 months.
JGH Open
January 2025
Division of Gastroenterology, Department of Medicine Chulalongkorn University Bangkok Thailand.
Background: Despite the popularity of a ketogenic diet, no randomized, controlled trials have evaluated its efficacy on metabolic dysfunction-associated steatotic liver disease (MASLD) progression.
Methods: We conducted an 8-week, open-label, randomized controlled trial involving 24 patients with MASLD who were randomly assigned to either the home delivery ketogenic diet or a nutrition education program on adherence to the DASH diet. The primary outcome was a reduction in hepatic steatosis as measured by transient elastography.
Curr Dev Nutr
January 2025
Department for Public Health, Aarhus University, Aarhus, Denmark.
Background: Carbohydrate restriction can alter substrate utilization and potentially impair endurance performance in female athletes. Caffeine intake may mitigate this performance decrements.
Objectives: The aim of this study was to test the hypothesis that maximal fat oxidation (MFO) rate would be enhanced in the carbohydrate (CHO) restricted state in trained females.
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