Purpose Of Review: Rehabilitation for patients with neuromuscular disorders (NMDs) has undisputed health benefits and is potentially therapeutic for targeting impairments, improving quality of life, and enabling activities of daily living. Whilst rehabilitation is commonly prescribed, unequivocal evidence and disease-related guidelines are lacking. This review highlights recent studies of exercise, assistive devices, respiratory management and manual therapy and stretching for patients with NMDs.
Recent Findings: Randomised controlled trials of neuromuscular rehabilitation are scant, often underpowered and lack a control group. Recent case studies, clinical trials and cohort studies support rehabilitative therapies such as exercise, respiratory muscle training, assistive devices, and manual therapy and stretching, to provide systemic health benefits, with the possibility to retain or improve function. No evidence of overwork weakness or muscle damage have been reported in exercise trials, and rehabilitative exercise programs in many cases lead to positive psychosocial impacts. Tele-rehab is an emerging area of interest, as a response to the COVID-19 pandemic.
Summary: Robust evidence for the benefits of neuromuscular rehabilitation is lacking, and clinical trial quality can be improved. Tele-rehab is a tantalising development to improve access to neuromuscular rehabilitation in both metropolitan and remote settings during and beyond the COVID-19 pandemic.
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http://dx.doi.org/10.1097/WCO.0000000000000974 | DOI Listing |
Int J Mol Sci
December 2024
Bone Pathophysiology Research Unit, Bambino Gesù Children's Hospital, IRCCS, 00146 Rome, Italy.
Laminopathies represent a wide range of genetic disorders caused by mutations in gene-encoding proteins of the nuclear lamina. Altered nuclear mechanics have been associated with laminopathies, given the key role of nuclear lamins as mechanosensitive proteins involved in the mechanotransduction process. To shed light on the nuclear partners cooperating with altered lamins, we focused on Src tyrosine kinase, known to phosphorylate proteins of the nuclear lamina.
View Article and Find Full Text PDFMedicina (Kaunas)
November 2024
Department of Sports Medicine, Medical University of Lublin, 20-093 Lublin, Poland.
: Sport climbing's popularity has grown with its inclusion in the Olympics and increased accessibility. Understanding the relationship between hand dominance, grip strength, endurance, and the involvement of masticatory and neck muscles can provide valuable insights into the neuromuscular adaptations specific to sport climbing, potentially aiding performance optimization and injury prevention in intermediate and advanced climbers. This study analyzes if the dominant hand has greater isometric endurance and isometric manual grip strength parameters than the non-dominant one and examines its relation to the masticatory and neck muscles in intermediate and advanced sport climbers.
View Article and Find Full Text PDFMedicina (Kaunas)
November 2024
Clinical Department of Geriatrics, Lithuanian University of Health Sciences, 44307 Kaunas, Lithuania.
: Oropharyngeal dysphagia is a common swallowing disorder, characterized by difficulties in moving food and liquids from the mouth to the esophagus; it is particularly prevalent among older adults with neurological conditions. This study aimed to evaluate the effectiveness of a short-term complex treatment protocol combining dietary modifications, swallowing exercises, and transcutaneous neuromuscular electrostimulation in reducing the oropharyngeal dysphagia severity and aspiration risk among geriatric patients. : A total of 64 participants aged 60 and older, with oropharyngeal dysphagia, at LSMU Kaunas Hospital between May 2021 and April 2023, were included in the study after excluding those with significant comorbidities.
View Article and Find Full Text PDFJ Clin Med
December 2024
Unit of Hand Surgery, Microsurgery and Reconstructive, Department of Orthopaedics and Traumatology, CTO Hospital, 10126 Turin, Italy.
Neonatal brachial plexus palsy (NBPP) is a flaccid paralysis of the upper limbs that occurs in about 0.4 percent of live births. This condition can produce permanent disabilities; to date, there is no consensus on protocols to be applied for the rehabilitation of children with this condition.
View Article and Find Full Text PDFJ Clin Med
December 2024
Unit of Musculoskeletal and Metabolic Rehabilitation, IRCCS Istituto Auxologico Italiano, 20095 Milan, Italy.
: This case study investigates the effect of a five-session whole-body cryostimulation (WBC) cycle on a 55-year-old female patient with cerebral palsy (CP) and lower limb spasticity (LLS) with a typical diplegic gait pattern. CP is a common physical disability characterized by motor impairments, including spasticity, which significantly impacts mobility and quality of life. The current treatments for spasticity often have limited efficacy and considerable side effects, making alternative therapies like WBC an area of interest.
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