Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8901817 | PMC |
| http://dx.doi.org/10.1007/s13238-021-00860-9 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Antler blood enhances the ability of stem cell-derived exosomes to promote bone and vascular regeneration.
Regen Ther
June 2024
School of Medicine, Xiamen University, Xiamen 361102, Fujian, China.
Background: Bone marrow mesenchymal stem cells (BMSC)-derived exosomes (Exos) are important in promoting bone and vascular regeneration. Antler blood (ALB) is a valuable traditional Chinese medicine with potent regenerative effects. However, there is still a lack of clarity regarding the relationship between ALB and BMSC-Exos.
View Article and Find Full Text PDFExosomes Derived from Antler Mesenchymal Stem Cells Promote Wound Healing by miR-21-5p/STAT3 Axis.
Int J Nanomedicine
November 2024
Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, Changchun, Jilin, 130112, People's Republic of China.
Background: Deer antlers, unique among mammalian organs for their ability to regenerate annually without scar formation, provide an innovative model for regenerative medicine. This study explored the potential of exosomes derived from antler mesenchymal stem cells (AMSC-Exo) to enhance skin wound healing.
Methods: We explored the proliferation, migration and angiogenesis effects of AMSC-Exo on HaCaT cells and HUVEC cells.
Repair of Mechanical Cartilage Damage Using Exosomes Derived from Deer Antler Stem Cells.
Front Biosci (Landmark Ed)
August 2024
Institute of Special Animal and Plant Sciences, Chinese Academy of Agricultural Sciences, 130112 Changchun, Jilin, China.
Background: Articular cartilage has limited self-repair capacity, and current clinical treatment options for cartilage defects are inadequate. However, deer antler cartilage possesses unique regenerative properties, with the ability to rapidly repair itself. This rapid self-repair process is closely linked to the paracrine factors released by deer antler stem cells.
View Article and Find Full Text PDFAntler stem cell-derived exosomes promote regenerative wound healing via fibroblast-to-myofibroblast transition inhibition.
J Biol Eng
November 2023
Institute of Antler Science and Product Technology, Changchun Sci-Tech University, No. 1345 of Pudong Rd., Changchun, Jilin, 130600, China.
Introduction: The typical outcome of mammalian wound healing is scarring, a fibrotic process mediated by myofibroblast aggregation. Perfect healing in a clinical setting is relatively unexplored. Surprisingly, our previous studies have shown that the large wound (10 cm diameter or more) of the pedicle of deer naturally achieves regenerative restoration, realized through a paracrine pathway from adjacent antler stem cells (AnSCs).
View Article and Find Full Text PDFDeer antlers: the fastest growing tissue with least cancer occurrence.
Cell Death Differ
December 2023
The Third Affiliated Hospital of Soochow University/The First People's Hospital of Changzhou, State Key Laboratory of Radiation Medicine and Protection, Institutes for Translational Medicine, Suzhou Medical College of Soochow University, Suzhou, China.
Deer antlers are a bony organ solely able to acquired distinct unique attributes during evolution and all these attributes are against thus far known natural rules. One of them is as the fastest animal growing tissue (2 cm/day), they are remarkably cancer-free, despite high cell division rate. Although tumor-like nodules on the long-lived castrate antlers in some deer species do occur, but they are truly benign in nature.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!