AI Article Synopsis
- A study investigated the effectiveness of abbreviated breast MRI for patients with suspicious microcalcifications detected on screening mammograms, including 80 patients undergoing the procedure before biopsy from August 2017 to September 2020.
- Results showed that abbreviated MRI significantly improved the positive predictive value (PPV) from 33.8% to 75.8%, indicating better accuracy in identifying true cases of malignancy.
- The use of abbreviated MRI also led to an 85% reduction in unnecessary biopsies for benign lesions, confirming its additional diagnostic value without missing invasive cancers.
Article Abstract
Objectives: To investigate the added diagnostic value of abbreviated breast magnetic resonance imaging (MRI) for suspicious microcalcifications on screening mammography.
Methods: This prospective study included 80 patients with suspicious calcifications on screening mammography who underwent abbreviated MRI before undergoing breast biopsy between August 2017 and September 2020. The abbreviated protocol included one pre-contrast and the first post-contrast T1-weighted series. MRI examinations were interpreted as either positive or negative based on the visibility of any significant enhancement. The positive predictive value (PPV) was compared before and after the MRI.
Results: Of the 80 suspicious microcalcifications, 33.8% (27/80) were malignant and 66.2% (53/80) were false positives. Abbreviated MRI revealed 33 positive enhancement lesions, and 25 and two lesions showed true-positive and false-negative findings, respectively. Abbreviated MRI increased PPV from 33.8 (27 of 80 cases; 95% CI: 26.2%, 40.8%) to 75.8% (25 of 33 cases; 95% CI: 62.1%, 85.7%). A total of 85% (45 of 53) false-positive diagnoses were reduced after abbreviated MRI assessment.
Conclusions: Abbreviated MRI added significant diagnostic value in patients with suspicious microcalcifications on screening mammography, as demonstrated by a significant increase in PPV with a potential reduction in unnecessary biopsy.
Key Points: • Abbreviated breast magnetic resonance imaging increased the positive predictive value of suspicious microcalcifications on screening mammography from 33.8 (27/80 cases) to 75.8% (25/33 cases) (p < .01). • Abbreviated magnetic resonance imaging helped avoid unnecessary benign biopsies in 85% (45/53 cases) of lesions without missing invasive cancer.
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| http://dx.doi.org/10.1007/s00330-021-08196-y | DOI Listing |
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