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The psychosis human connectome project: An overview. | LitMetric

The psychosis human connectome project: An overview.

Neuroimage

Department of Psychiatry and Behavioral Sciences, University of Minnesota, Minneapolis, MN, United States; Department of Psychology, University of Minnesota, Minneapolis, MN, United State; Minneapolis Veterans Affairs Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, United State. Electronic address:

Published: November 2021

AI Article Synopsis

  • The Human Connectome Project is studying brain disorders, especially focusing on psychotic problems through the Psychosis Human Connectome Project (P-HCP).
  • They gathered lots of different types of data, like MRI scans, clinical assessments, and blood samples from participants to learn more about these brain issues.
  • The information collected will be shared publicly, so other researchers can use it to explore and understand psychotic disorders better.

Article Abstract

Investigations within the Human Connectome Project have expanded to include studies focusing on brain disorders. This paper describes one of the investigations focused on psychotic psychopathology: The psychosis Human Connectome Project (P-HCP). The data collected as part of this project were multimodal and derived from clinical assessments of psychopathology, cognitive assessments, instrument-based motor assessments, blood specimens, and magnetic resonance imaging (MRI) data. The dataset will be made publicly available through the NIMH Data Archive. In this report we provide specific information on how the sample of participants was obtained and characterized and describe the experimental tasks and procedures used to probe neural functions involved in psychotic disorders that may also mark genetic liability for psychotic psychopathology. Our goal in this paper is to outline the data acquisition process so that researchers intending to use these publicly available data can plan their analyses. MRI data described in this paper are limited to data acquired at 3 Tesla. A companion paper describes the study's 7 Tesla image acquisition protocol in detail, which is focused on visual perceptual functions in psychotic psychopathology.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8542422PMC
http://dx.doi.org/10.1016/j.neuroimage.2021.118439DOI Listing

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