Background: Onychoheterotopia, or ectopic nail, is a rare nail condition in which nail growth occurs in areas other than the distal phalanges. The majority of cases in the literature are noted to be congenital; however, acquired cases have less commonly been described following either acute or chronic trauma.
Methods: We present a case of acquired onychoheterotopia in a child, with a corresponding literature review of acquired pediatric onychoheterotopia cases for comparison.
Results: There were a total of 10 cases of acquired onychoheterotopia in pediatric patients in the literature. Including our patient, 81.8% (9/11) developed an ectopic nail on the fingers. Crush injury preceded the ectopic nails in 45.5 % (5/11) of cases. Infection occurred in 27.3% (3/11).
Conclusions: Although the incidence and prevalence of acquired onychoheterotopia are unknown, it seems to be an uncommon phenomenon. From our case and others from the literature, there may be associations with crush injury specifically. Further research will be needed to fully elucidate the pathophysiology and risk factors for ectopic nail growth.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1111/pde.14702 | DOI Listing |
Am J Med Genet A
December 2024
Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", Trieste, Italy.
Alteration in the ubiquitin-proteasome system results in human disorders with neurological and/or autoinflammatory presentation. Haploinsufficiency of PSMD12, which encodes a subunit of the core component of the proteasome, causes Stankiewicz-Isidor syndrome (STISS), characterized by intellectual disability, autism spectrum disorder, craniofacial dysmorphisms, with or without other congenital anomalies, and autoinflammation. We described six patients (four adults) from two unrelated families carrying a known p.
View Article and Find Full Text PDFInt J Surg Case Rep
November 2024
Department of Dermatology, Faculty of Medicine, University of Aleppo, Aleppo, Syria.
Introduction And Importance: Post-traumatic ectopic nail (PTEN) refers to the abnormal growth of a new nail in a site other than the usual one, typically occurs after a trauma to the nail matrix. The exact pathogenesis is still unknown. This rare condition often affects the dorsal aspect of the phalanx.
View Article and Find Full Text PDFArthritis Res Ther
January 2024
Rheumatology Department, Hospital Clinic of Barcelona, Barcelona, Spain.
Background: Inflammatory arthritis encompasses a group of immune-mediated diseases characterized by chronic joint inflammation. Despite having pathogenic mechanisms in common, the prognosis of rheumatoid arthritis (RA), psoriatic arthritis (PsA), and undifferentiated arthritis (UA) could be different regarding progression to chronic, to erosive, or to self-limited disease. Our aim was to evaluate the potential association of synovial tissue (ST) inflammatory cell infiltrate, the presence of ectopic lymphoid neogenesis (LN +) structures, and poor prognosis factors (PPF) in patients with RA, PsA, and UA.
View Article and Find Full Text PDFBMC Pediatr
August 2023
Department of Nephrology and Rheumatology, Zhengzhou Key Laboratory of Pediatric Kidney Disease Research, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, 450018, China.
JAAD Case Rep
September 2023
Department of Dermatology, University of Michigan, Ann Arbor, Michigan.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!