Garcimckeans A-C, three new xanthones from the stems of , and their cytotoxic activity.

Three new xanthones, garcimckeans A-C () were isolated from the methanol extract of the stems of (Clusiaceae). Their structures were established by extensive spectroscopic analysis (HR-ESI-MS and 1 D and 2 D NMR) and by comparison of the spectral data with those reported in the literature. Compounds displayed weak cytotoxic activity toward KB, Lu, HepG2, and MCF7 cell lines using the MTT assay with IC values ranging from 71.03 ± 2.93 to 90.40 ± 7.13 µM compared to that of the positive control compound, ellipticine (IC: 1.22 ± 0.10 ∼ 2.44 ± 0.2 µM).