Diagnosis of synchronous multiple primary lung cancers (SMPLCs) is a challenge as multiple lesions on chest CT imaging can be misdiagnosed as more common entities such as metastatic disease or infections. The possibility of multiple primary lung cancers should always be considered. Accurate diagnosis can significantly change the management and prognosis. We report a case of a 57-year-old woman, an ex-smoker with chronic obstructive pulmonary disease (COPD), who was found to have synchronous endobronchial carcinoid tumor and adenocarcinoma of the lung. The association of carcinoid tumors and adenocarcinoma of the lung has been infrequently reported, with only a handful of cases published to date. Early diagnosis of resectable tumors can improve survival in patients with SMPLCs.
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http://dx.doi.org/10.7759/cureus.15977 | DOI Listing |
Cureus
November 2024
Respiratory Medicine, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, GBR.
Breast cancer is the most prevalent cancer among women worldwide. Despite significant advancements in breast cancer treatments over the past decade, late recurrence, a hallmark of breast cancer, remains a major challenge for oncologists. In this case report, we present an atypical presentation of late breast cancer recurrence as a peri-bronchial lesion manifesting as dysphagia 14 years after completing treatment for primary breast cancer.
View Article and Find Full Text PDFAm J Transl Res
May 2024
State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine Guangzhou 510060, Guangdong, The People's Republic of China.
Objective: This study aimed to assess the efficacy of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in detecting intrathoracic lymph nodes in patients with nasopharyngeal carcinoma (NPC).
Methods: Retrospective data analysis was conducted on individuals who underwent EBUS-TBNA between June 2015 and June 2022. Patients with NPC and enlarged intrathoracic lymph nodes were included.
Lung Cancer Manag
December 2023
Department of Respiratory Medicine, Craigavon Area Hospital, Southern Health & Social Care Trust, 68 Lurgan Road, Portadown, County Armagh, Northern Ireland, BT63 5QQ, UK.
Aim: Multiple primary lung cancers are becoming increasingly recognised and pose diagnostic and staging uncertainties with challenging management options and prognostication.
Case Report: We describe a case of synchronous multiple primary lung cancer occurring bilaterally, and the steps in reaching the diagnosis, initial surgical management, the intensive follow-up this underwent, and how its subsequent recurrence led to treatment with radiation therapy in light of the patient's declining fitness.
Discussion: This case highlighted that cytological recurrence could occur prior to radiological recurrence, especially for endobronchial tumors, and intensive follow-up both radiologically and endoscopically with multidisciplinary input is crucial in the management of these challenging cases where evidence-based guidelines are limited.
AME Case Rep
January 2023
Department of Pulmonary Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Background: Peripheral pulmonary nodules are often detected as multiple nodules in one patient. Computed tomography (CT) guided transthoracic biopsy (TTNB) is the most widely implemented method for minimal invasive biopsy of pulmonary nodules, but generally only one nodule is sampled per procedure. Navigation bronchoscopy is an endobronchial procedure with very low complication rates, and uses high-end image guidance which allows for the sampling of multiple nodules in one session, while also allowing inspection of the central airways and endobronchial ultrasound (EBUS) guided staging in one session.
View Article and Find Full Text PDFWorld J Clin Cases
December 2022
Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing 100142, China.
Background: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for the diagnosis of mediastinal and hilar lymph is poorly studied in patients with extrathoracic malignancies.
Aim: To evaluate the value of EBUS-TBNA for the diagnosis of enlarged intrathoracic lymph nodes in patients with extrathoracic malignancies.
Methods: This was a retrospective study of patients with extrathoracic malignancies who were referred to Peking University Cancer Hospital from January 2013 to December 2018 for EBUS-TBNA due to intrathoracic lymphadenopathy.
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