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| http://dx.doi.org/10.5114/aoms/136344 | DOI Listing |
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Is Intestinal Microbiota Fully Restored After Chickens Have Recovered from Coccidiosis?
Pathogens
January 2025
Department of Animal and Food Sciences, Oklahoma State University, Stillwater, OK 74078, USA.
The intestinal microbiota is known to be altered by -induced coccidiosis, but it remains unclear whether the microbiota is fully restored after recovery. To address this, 110 newly hatched Cobb male broiler chickens were challenged with 2 × 10 sporulated oocysts of (EM) strain M6 or mock-infected with saline on day 10. Body weight and feed intake were recorded.
View Article and Find Full Text PDFCombining Advanced Targeted Therapy in Inflammatory Bowel Disease: Current Practice and Future Directions.
J Clin Med
January 2025
IBD Unit, Gastroenterology Unit, Rho Hospital, ASST Rhodense, 20017 Rho, Italy.
Despite the increasing number of available medications, a significant proportion of IBD patients fail to achieve the current therapeutic targets. Uncontrolled IBD has a significant impact on patients' quality of life and on overall costs for the healthcare system. Given the complex pathophysiology of IBD, Combined Advanced Targeted Therapy (CATT), involving the combination of biologics/small molecules, appears to have biological plausibility and is gaining increasing interest.
View Article and Find Full Text PDFProbiotic Bacterium-Derived p40, p75, and HM0539 Proteins as Novel Postbiotics and Gut-Associated Immune System (GAIS) Modulation: Postbiotic-Gut-Health Axis.
Microorganisms
December 2024
Institute of Physiology, Medical School, University of Pécs, H-7624 Pécs, Hungary.
It is known that probiotics have direct and indirect effects on many systems in the body, especially the gastrointestinal system. Interest in using probiotic strain-derived cell components and metabolites has also increased as a result of the significant benefits of probiotics. Although many terminologies and definitions are used for these components and metabolites, the International Scientific Association of Probiotics and Prebiotics (ISAPP) recommended the use of the term postbiotic in 2021, which is defined as "a preparation of inanimate microorganisms and/or their components that confers a health benefit on the host".
View Article and Find Full Text PDFButyrate Supplementation Improves Intestinal Health and Growth Performance in Livestock: A Review.
Biomolecules
January 2025
School of Agricultural Science and Engineering, Liaocheng University, Liaocheng 252000, China.
Butyrate supplementation has gained considerable attention for its potential benefits in livestock, particularly concerning intestinal health and growth performance. This review synthesizes recent research on the diverse roles of butyrate, across various livestock species. As a short-chain fatty acid, butyrate is known for enhancing intestinal development, improving immune function, and modulating microbial diversity.
View Article and Find Full Text PDFSymptoms in Persons With Either Active or Inactive Crohn's Disease Are Agnostic to Disease Phenotype: The Magic in Imagine Study.
J Clin Gastroenterol
January 2025
Department of Medicine, McMaster University, Hamilton, ON, Canada.
Background: We aimed to examine the relationship between disease symptoms and disease phenotype in a large Canadian cohort of persons with Crohn's disease (CD).
Methods: Adults (n=1515) with CD from 14 Canadian centers participated in the Mind And Gut Interactions Cohort (MAGIC) between 2018 and 2023. Disease activity was measured using the 24-item IBD Symptom Inventory-Short-Form (IBDSI-SF).
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