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| http://dx.doi.org/10.1016/j.mjafi.2021.02.011 | DOI Listing |
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Clinical characteristics and risk factors for in-hospital mortality of COVID-19 patients in Hubei Province: A multicenter retrospective study.
Int J Cardiol Heart Vasc
February 2025
Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology; Hubei Key Laboratory of Genetics and Molecular Mechanisms of Cardiological Disorders, Wuhan 430030, China.
Background: Coronavirus disease (COVID-19) remains one of the most significant factors threatening public health security worldwide. The COVID-19 pandemic has been ongoing for more than 3 years; however, there are few studies on the clinical characteristics and mortality risk factors in patients with COVID-19 based on comprehensive data from multiple centers.
Methods: A total of 53,030 patients with confirmed COVID-19 from 138 hospitals in Hubei Province were included in this study.
Prediction of hospitalization time probability for COVID-19 patients with statistical and machine learning methods using blood parameters.
Ann Med Surg (Lond)
December 2024
Department of Computer Science, Faculty of Mathematical Sciences, University of Guilan, Rasht, Iran.
Objectives: Coronavirus disease 2019 (COVID-19) may induce life-threatening complications and lead to death in the patients.
Method: The aim of this study was to describe a predictive model for the disease outcome (length of hospitalization and mortality) by using blood parameters results at the admission time of 201 patients with positive RT-PCR test for the infection. Variables including; age, sex, comorbidity risk factors, the length of hospitalization, and 25 blood parameters results at the time of admission were considered.
Impact of Hyponatremia and ADH Secretion in MIS-C and COVID-19: An Integrative Approach of Prognostic and Diagnostic Markers.
Curr Issues Mol Biol
October 2024
Faculty of Medicine and Pharmacy, University "Dunarea de Jos" of Galati, 800201 Galati, Romania.
The COVID-19 pandemic has introduced challenges in pediatric care, especially due to the emergence of Multisystem Inflammatory Syndrome in Children (MIS-C), a severe condition associated with SARS-CoV-2 infection. This study investigated the impact of hyponatremia and antidiuretic hormone (ADH) secretion corelated to clinical outcomes in these patients. We conducted a retrospective cohort study, including 118 pediatric patients, with a detailed sub-cohort analysis of 53 patients for ADH secretion markers.
View Article and Find Full Text PDFCoronavirus Disease 2019 (COVID-19)-Induced Hyponatremia: A Challenging Geriatric Case.
Cureus
October 2024
Family Medicine, Beckley Appalachian Regional Healthcare (ARH) Hospital, Beckley, USA.
Article Synopsis
- * Initial thoughts about her condition pointed to improper regulation of water in the body, but further investigation indicated that her symptoms might be due to poor fluid intake and a misdiagnosed kidney issue.
- * The patient's liver enzyme levels improved with supportive treatment, allowing for the use of remdesivir, and her sodium levels gradually stabilized, underscoring the need for tailored patient management during COVID-19 recovery.
Hyponatremia unleashes neutrophil extracellular traps elevating life-threatening pulmonary embolism risk.
Proc Natl Acad Sci U S A
November 2024
Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan.
Neutrophil extracellular traps (NETs), essential for controlling infections, can induce various pathologies when dysregulated. Known triggers for infection-independent NETs release exist, yet a comprehensive understanding of the conditions prompting such responses is lacking. In this study, we identify hyponatremia as an independent inducer of NETs release, a common clinical condition that disrupts sodium/calcium exchange within neutrophils.
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