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| http://dx.doi.org/10.1016/j.jinf.2021.07.027 | DOI Listing |
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Deciphering long-term immune effects of HIV-1/SARS-CoV-2 co-infection: a longitudinal study.
Med Microbiol Immunol
December 2024
Immunology Section, Molecular Immuno-Biology Laboratory, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain.
Introduction: While the general immune response to Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) is well-understood, the long-term effects of Human Immunodeficiency Virus-1/Severe Acute Respiratory Syndrome-Coronavirus-2 (HIV-1/SARS-CoV-2) co-infection on the immune system remain unclear. This study investigates the immune response in people with HIV-1 (PWH) co-infected with SARS-CoV-2 to understand its long-term health consequences.
Methods: A retrospective longitudinal study of PWH with suppressed viral load and SARS-CoV-2 infection was conducted.
Background: Vaccination has been shown to attenuate the risk of post-acute sequelae following SARS-CoV-2 infection. However, no prior population-based studies have evaluated if updated bivalent boosters reduce risk of post-acute sequelae following Omicron-variant infection, versus ancestral vaccines.
Methods: National databases were utilised to construct a population-based cohort of adult individuals infected during Omicron-predominant transmission.
Insight into potential long COVID effects: Antidepressant use in post SARS-CoV-2 Infection scenarios. A multiregional nested case-control study.
Psychiatry Res
November 2024
Università Cattolica del Sacro Cuore, Rome, Italy; Fondazione Policlinico Gemelli IRCCS, Rome, Italy.
This study aimed to investigate the impact of previous SARS-CoV-2 infection and the role of vaccination in the onset of neuropsychiatric conditions, evaluated through antidepressant prescriptions. This case-control study evaluated the risk of new antidepressant prescriptions in relation to previous exposure to SARS-CoV-2 infection and vaccination. It was conducted in three Italian Regions on adults who did not receive antidepressant prescriptions in the year preceding the study period.
View Article and Find Full Text PDFLatent class analysis of post-acute sequelae of SARS-CoV-2 infection.
J Biopharm Stat
November 2024
Pfizer Inc, New York, New York, USA.
Symptoms post-SARS-CoV-2 infection may persist for months and cause significant impairment and impact to quality of life. Acute symptoms of SARS-CoV-2 infection are well studied, yet data on clusters of symptoms over time, or post-acute sequelae of SARS-CoV-2 infection (PASC), are limited. We aim to characterize PASC phenotypes by identifying symptom clusters over a six-month period following infection in individuals vaccinated (boosted and not) and those unvaccinated.
View Article and Find Full Text PDFPostural orthostatic tachycardia syndrome after COVID-19 vaccination: A systematic review.
BMC Cardiovasc Disord
November 2024
University Center for Research and Development, Chandigarh University, Mohali, Punjab, India.
Article Synopsis
- The COVID-19 vaccination campaign has successfully reduced severe illness and mortality, but concerns about potential side effects like Postural Orthostatic Tachycardia Syndrome (POTS) have emerged.
- A systematic review examined studies of POTS post-vaccination, with 10 out of 1,531 articles meeting inclusion criteria, involving nearly 285,000 participants.
- Results indicated that while the odds of developing POTS after vaccination are lower compared to post-infection, research is still limited and further studies are necessary.
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