Global industrialization and urbanization have led to increased levels of air pollution. Those with respiratory diseases, such as asthma, are at the highest risk for adverse health effects and reduced quality of life. Studying the relationship between pollutants and symptoms is usually achieved with data from government air quality monitoring stations, but these fail to report the spatial and temporal resolution required to track a person's true exposure, especially when the majority of their time is spent indoors. We develop and build eight wrist-worn wearable devices, weighing only 64 g, to measure known asthma symptom triggers: ozone, total volatile organic compounds, temperature, humidity, and activity level. The devices use commercial off-the-shelf components, costing under $150 each to build. This report focuses on the design, calibration, and testing of the devices. Emphasis is placed on the calibration of a metal-oxide-semiconductor gas sensor for detecting ozone, which is a difficult task because of the large variations in ambient temperature and humidity found when using a wearable device. Examples of testing the devices in four real environments are also discussed: 11 days inside a well-ventilated laboratory, ten days outdoors during the summer, alternating the devices between indoor and outdoor environments to examine their response to quickly changing environments, and a field test where scripted activities are performed for a full day. The work demonstrates a wearable device for environmental health studies and addresses the challenges of existing sensors for real-world applications.
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http://dx.doi.org/10.1109/jsen.2019.2917435 | DOI Listing |
JAMA Netw Open
January 2025
Transformative Health Systems Research to Improve Veteran Equity and Independence Center of Innovation, Veterans Affairs Providence Health Care System, Providence, Rhode Island.
Importance: Influenza vaccination remains the most important intervention to prevent influenza morbidity and mortality among nursing home residents. The additional effectiveness of recombinant influenza vaccine vs standard dose vaccines was demonstrated in outpatient older adults but has not been evaluated in nursing home populations.
Objective: To compare hospitalization rates among residents in nursing homes immunized with a recombinant vs a standard dose egg-based influenza vaccine.
Eur J Pediatr
January 2025
Alliance of Dutch Burn Care, Burn Center, Red Cross Hospital, PO Box 1074, 1940 EB, Beverwijk, the Netherlands.
Unlabelled: Knowledge about trends and epidemiology of pediatric burns is useful to identify patterns, to advance medical research, and to design prevention programs and resource allocation. The aim of this study is to describe the epidemiology and trends of pediatric burns between 2009 and 2022 in the three Dutch burn centers. A secondary objective of this study is to evaluate the influence of the COVID-19 pandemic on the pattern of pediatric burns.
View Article and Find Full Text PDFFunct Integr Genomics
January 2025
Department of Clinical Laboratory, the Fourth Affiliated Hospital of School of medicine, International Institutes of Medicine, Zhejiang University, Yiwu, China.
Since December 2019, the global dissemination of a novel coronavirus has precipitated a notable public health crisis, prompting considerable interest and scrutiny from governmental and scholarly entities. Substantial research efforts have been dedicated to exploring diverse facets of this novel coronavirus, encompassing its pathogenesis, transmission dynamics, and therapeutic interventions. Recent findings suggest that circular RNAs (circRNAs) exert a pivotal influence on modulating viral infectivity and immune defense mechanisms.
View Article and Find Full Text PDFAm J Manag Care
December 2024
University of Missouri Truman School of Government and Public Affairs, 615 Locust St, E004 Locust Street Bldg, Columbia, MO 65211. Email:
Objectives: To assess the capacity of Medicaid providers to take on new patients during a time of unprecedented growth in program enrollment due to Medicaid expansion and the COVID-19 public health emergency.
Study Design: We conducted a survey of Medicaid providers in Missouri in 2023 about their patient load and capacity to accept new patients.
Methods: We recruited 141 Missouri Medicaid providers through probability sampling and 109 additional providers through convenience sampling for a total sample size of 250, representing 0.
J Virol
December 2024
Department of Microbiology, University of Washington School of Medicine, Seattle, Washington, USA.
Unlabelled: Due to the importance of post-translational modification (PTM) in cellular function, viruses have evolved to both take advantage of and be susceptible to such modification. Adenovirus encodes a multifunctional protein called protein VII, which is packaged with the viral genome in the core of virions and disrupts host chromatin during infection. Protein VII has several PTMs whose addition contributes to the subnuclear localization of protein VII.
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