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Inflammatory biomarkers as cost-effective predictive tools in metabolic dysfunction-associated fatty liver disease.
World J Gastroenterol
December 2024
Department of Internal Medicine, University of Genoa, Genoa 16132, Italy.
Qu and Li emphasize a fundamental aspect of metabolic dysfunction-associated fatty liver disease in their manuscript, focusing on the critical need for non-invasive diagnostic tools to improve risk stratification and predict the progression to severe liver complications. Affecting approximately 25% of the global population, metabolic dysfunction-associated fatty liver disease is the most common chronic liver condition, with higher prevalence among those with obesity. This letter stresses the importance of early diagnosis and intervention, especially given the rising incidence of obesity and metabolic syndrome.
View Article and Find Full Text PDFBurden of thyroid cancer in China and worldwide from 1990 to 2021: observation, comparison, and forecast from the Global Burden of Disease Study 2021.
Front Endocrinol (Lausanne)
December 2024
Department of General Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Background: Thyroid cancer (TC) is a prevalent malignant tumor of the endocrine system in China. Current research primarily focuses on clinical diagnosis and treatment as well as underlying mechanisms, lacking epidemiological studies on the burden of the disease in China and worldwide.
Methods: The Global Burden of Disease Study 2021 was utilized to assess the incidence, prevalence, death, and disability-adjusted life years of TC in China and worldwide from 1990 to 2021 using the Joinpoint and R software.
Cost-effectiveness of camrelizumab plus rivoceranib for advanced hepatocellular carcinoma in the context of regional disparities in China.
Front Oncol
December 2024
Department of Oncology, Binzhou Medical University Hospital, Binzhou, Shandong, China.
Objective: To assess the cost-effectiveness of combining camrelizumab with rivoceranib versus sorafenib as initial treatment options for advanced hepatocellular carcinoma (HCC) across different developmental regions in China.
Methods: Utilizing TreeAge Pro and data from the phase III randomized CARES-310 clinical trial, a model based on Markov state transitions was developed. Health state utility values were derived from the CARES-310 trial, and direct medical costs were obtained from relevant literature and local pricing data.
Digital health applications in Germany: Explorative pilot study on the challenges of approval from the perspective of manufacturers.
Digit Health
December 2024
Faculty of Health Sciences, University of Applied Sciences, Giessen, Germany.
Objective: Digital health applications are digital medical products (e.g. apps and web applications) that are prescribed by healthcare service providers and reimbursed by health insurances.
View Article and Find Full Text PDFFluorescent Staining-Assisted Evaluation of the Anticancer Potential of Nyctanthes arbor-tristis Extracts in HepG2 Liver Cancer Cells.
Luminescence
December 2024
Department of Physics and Astronomy, College of Science, King Saud University, Riyadh, Saudi Arabia.
The current study's initial goal was to investigate the anticancer activity of the extracts from the flowering plant Nyctanthes arbor-tristis. The ethanol extracts' phytochemical analysis was qualitatively determined. It was determined that the various phytochemical substances had antibacterial, antioxidant, and anticancer effects.
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