Background: Cranioplasty can be carried out using either fresh, frozen autologous bone or synthetic substitutes. Ordering artificial 3 dimensional (3D) implants is challenging and time consuming depending on geographical location. In this article, we share our experience using a streamlined process of producing 3D computer-assisted design (CAD) implants using commercially available 3D printers and silicone molds that can be easily replicated with consistent results and are associated with good outcomes.
Objective: To develop patient-specific implants for patients with cranial defects that are accurate, consistent, low cost, and easy to replicate while reducing operator-dependent factors.
Methods: We present data from 15 patients who underwent cranioplasty with 3D CAD-designed gentamicin-impregnated bone cement implants that were molded using the cold injection technique.
Results: The technique was consistent in result production, required little postdemolding manipulation, and showed no dimensional variation in design. Postoperative computed tomography scans showed excellent implant fit, and patients had a low complication rate.
Conclusion: We have demonstrated a technique of mold preparation that is efficient and that produces a reliable result. Polymethyl methacrylate implants molded using this technique showed better reproducibility, higher accuracy, and precision than other types of implants and required minimal postdemolding clean-up.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/ons/opab257 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
MicroMetaSense: Coupling Plasmonic Metasurfaces with Fluorescence for Enhanced Detection of Microplastics in Real Samples.
ACS Sens
December 2024
UNAM-National Nanotechnology Research Center, Bilkent University, 06800 Ankara, Turkey.
Diverse analytical techniques are employed to scrutinize microplastics (MPs)─pervasive at hazardous concentrations across diverse sources ranging from water reservoirs to consumable substances. The limitations inherent in existing methods, such as their diminished detection capacities, render them inadequate for analyzing MPs of diminutive dimensions (microplastics: 1-5 μm; nanoplastics: < 1 μm). Consequently, there is an imperative need to devise methodologies that afford improved sensitivity and lower detection limits for analyzing these pollutants.
View Article and Find Full Text PDFInnovative Polymeric Biomaterials for Intraocular Lenses in Cataract Surgery.
J Funct Biomater
December 2024
Department of Surgery, Division of Ophthalmology, University of Sherbrooke, Sherbrooke, QC J1G 2E8, Canada.
Intraocular lenses (IOLs) play a pivotal role in restoring vision following cataract surgery. The evolution of polymeric biomaterials has been central to addressing challenges such as biocompatibility, optical clarity, mechanical stability, and resistance to opacification. This review explores essential requirements for IOL biomaterials, emphasizing their ability to mitigate complications like posterior capsule opacification (PCO) and dysphotopsias while maintaining long-term durability and visual quality.
View Article and Find Full Text PDFAn In Vitro Study to Assess the Effect of Cigarette Smoke on Color Stability and Surface Roughness of 3D Printed, Milled, and Traditional Provisional Crown and Bridge Materials.
Cureus
November 2024
General Dentistry and Comprehensive Care, NYU College of Dentistry, New York University, New York, USA.
Objectives To assess the influence of cigarette smoke (CS) on the color and surface roughness of 3D printed, milled, and traditionally fabricated provisional crown and bridge (PC&B) materials. Materials and methods 112 disc-shaped samples were made employing four techniques and materials (28 per group) to fabricate PC&B prostheses. Specimens were fabricated using standard protocols, such as 3D printing, milling, conventional bis-acrylic resin, and traditional autopolymerizing polymethyl methacrylate (PMMA) resin.
View Article and Find Full Text PDFA Case Report Describing the Surgical Removal of Venous and Intracardiac Cement Leakage after Percutaneous Vertebroplasty in a Hybrid Operating Room.
Ann Ital Chir
December 2024
Department of Cardiovascular Surgery, Centro Cardiologico Monzino IRCCS, 20138 Milan, Italy; Department of Biomedical, Surgical, and Dental Sciences, University of Milan, 20122 Milan, Italy.
Aim: Percutaneous vertebroplasty is generally considered a safe procedure, however, cases of cardioembolism and cardiac perforation have been reported.
Case Presentation: A 69-year-old woman was referred to our emergency department after an outpatient echocardiogram revealed a "thrombus-like" formation involving the right heart. Two weeks before she had undergone percutaneous vertebroplasty of the third to fifth lumbar vertebrae due to osteoporotic fractures.
Microfluidics-Driven Manufacturing and Multiscale Analytical Characterization of Nanoparticle-Vesicle Hybrids.
Adv Healthc Mater
December 2024
ETH Zürich, Department of Chemistry and Applied Biosciences, Institute for Chemical and Bioengineering, 8093, Zürich, Switzerland.
Coating synthetic nanoparticles (NPs) with lipid membranes is a promising approach to enhance the performance of nanomaterials in various biological applications, including therapeutic delivery to target organs. Current methods for achieving this coating often rely on bulk approaches which can result in low efficiency and poor reproducibility. Continuous processes coupled with quality control represent an attractive strategy to manufacture products with consistent attributes and high yields.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!