Objective: Chronic health conditions (CHC) can have severe impacts on an individual's life, affecting well-being and mental health. Nonetheless, individuals can show different response patterns of psychological adaptation following a CHC onset. This study aimed to identify profiles of subjective well-being (SWB) at 1 year before (T - 1), 1 year after (T + 1), and 4 years after (T + 4) the onset of a physical CHC using seven indicators (health satisfaction, life satisfaction, energy, joy, worry, sadness, anger), examine transitions between the identified profiles, and determine predicting factors of these transitions.
Method: Latent profile analysis and latent transition analysis was conducted using a sample of 357 participants reporting a physical CHC drawn from the Swiss Household Panel dataset.
Results: Three profiles were identified at T - 1: low, high, and very high SWB. At T + 1 and T + 4, a fourth vulnerable profile emerged. Transition analysis showed that, overall, the most probable transition was to stay in similar profiles across time. However, recovery toward higher SWB profiles and delayed reaction toward lower SWB profiles appeared between 1 and 4 years following the CHC onset. Factors predicting recovery patterns from low to high SWB are better health status, fewer negative life events, and financial scarcity, whereas lower emotional stability was related to a delayed reaction from high to low SWB.
Conclusion: This study underlines the importance of personal factors in the adaptation following CHC onset. Routine assessment of personality traits would enable identifying individuals at greater risk of lower SWB following the onset of a CHC. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
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http://dx.doi.org/10.1037/hea0001090 | DOI Listing |
J Biomed Sci
January 2025
Graduate Institute of Microbiology, National Taiwan University College of Medicine, Taipei, Taiwan.
Background: In regions with a high prevalence of chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections, coinfected patients face a heightened risk of developing hepatocellular carcinoma (HCC), termed HBV/HCV-related HCC (HBCV-HCC). We aimed to investigate the contribution of preexisting chronic hepatitis B (CHB) and subsequent chronic hepatitis C (CHC) to the development of HBCV-HCC.
Methods: We examined HBV's involvement in 93 HBCV-HCC cases by analyzing HBV DNA integration as an indicator of HCC originating from HBV-infected hepatocytes, compared with 164 HBV-HCCs and 56 HCV-HCCs as controls.
Sensors (Basel)
December 2024
EXOForce Robotics, Arlington, VA 22209, USA.
Freezing of gait (FOG) is a disabling yet poorly understood paroxysmal gait disorder affecting the vast majority of patients with Parkinson's disease (PD) as they reach advanced stages of the disorder. Falling is one of the most disabling consequences of a FOG episode; it often results in injury and a future fear of falling, leading to diminished social engagement, a reduction in general fitness, loss of independence, and degradation of overall quality of life. Currently, there is no robust or reliable treatment against FOG in PD.
View Article and Find Full Text PDFInfect Dis Ther
November 2024
Universidade Federal do Paraná (UFPR), 181, General Carneiro Street, Curitiba, PR, Brazil.
Introduction: Amphotericin B lipid complex (ABLC) is an effective antifungal agent for treating invasive fungal infections (IFIs) even though its formulation is associated with potential adverse events, including those related to its infusion. This study aimed to analyze the incidence of acute infusion-related side effects (IRSE) associated with ABLC and their relationship with the profile of patients with oncohematological disease admitted in Brazilian reference tertiary hospitals.
Methods: This is an observational retrospective study that included clinical records of patients hospitalized, in a period of 6 years, diagnosed with probable or proved IFI and treated with at least two doses of ABLC.
Cureus
October 2024
Dermatology, Calcutta National Medical College and Hospital, Kolkata, IND.
Dupilumab is the first US FDA-approved biologic for moderate to severe atopic dermatitis (AD) in adults and children of age more than six months. It is a fully monoclonal antibody that inhibits interleukin (IL)-4 and IL-13 signal transmission. The initial product monograph mentioned major side effects like hypersensitivity reactions and eye problems like conjunctivitis, dry eye, and keratitis.
View Article and Find Full Text PDFInfect Drug Resist
October 2024
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People's Republic of China.
Hepatocellular carcinoma (HCC) is one of the most prevalent malignant tumors globally. Prominent factors include chronic hepatitis B (CHB) and chronic hepatitis C (CHC) virus infections, exposure to aflatoxin, alcohol abuse, diabetes, and obesity. The prevalence of hepatitis B (HBV) is substantial, and the significant proportion of asymptomatic carriers heightens the challenge in diagnosing and treating hepatocellular carcinoma (HCC), necessitating further and more comprehensive research.
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