Objective: Sexual and gender minority people of color (SGM-POC) report higher rates of intimate partner violence (IPV) than White SGM, adding to growing evidence that people holding multiple stigmatized social identities are at particular risk for adverse experiences. We aimed to identify mechanisms underlying the racial/ethnic disparities in IPV among SGM, focusing on childhood experiences of violence, structural inequalities, and sexual minority stress.
Method: 308 SGM assigned female-at-birth (AFAB; 82 White, 133 Black, 93 Latinx; age 16-31) self-reported on minor psychological, severe psychological, physical, and sexual IPV victimization and perpetration, and three proposed mechanisms: childhood violence (child abuse, witnessing interparental violence), structural inequalities (economic stress, racial discrimination), and sexual minority stressors (internalized heterosexism, anti-SGM victimization, low social support). Indirect effects of race on IPV victimization via hypothesized mechanisms were estimated using logistic regression with 5,000 bootstrapped samples.
Results: Compared to White participants, Black participants were 2.5-7.03 times more likely to report all eight IPV types; Latinx participants were 2.5-4.8 times more likely to experience four IPV types. Univariate indirect effects analyses indicated that these racial/ethnic disparities were partially explained by higher economic stress, racial/ethnic discrimination, and childhood violence experiences (for Black and Latinx participants) and lower social support (Black participants). In multivariate models, the most robust indirect effects were through racial/ethnic discrimination and childhood violence.
Conclusions: Findings underscore the need for policy and interventions aimed at preventing IPV among SGM-POC by targeting factors that contribute to IPV disparities in this group, particularly racial/ethnic discrimination and family violence. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
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http://dx.doi.org/10.1037/cdp0000463 | DOI Listing |
Mol Psychiatry
January 2025
Telethon Institute of Genetics and Medicine, Via Campi Flegrei 34, Pozzuoli, 80078, Naples, Italy.
Lysosomal storage disorders characterized by defective heparan sulfate (HS) degradation, such as Mucopolysaccharidosis type IIIA-D (MPS-IIIA-D), result in neurodegeneration and dementia in children. However, dementia is preceded by severe autistic-like behaviours (ALBs), presenting as hyperactivity, stereotypies, social interaction deficits, and sleep disturbances. The absence of experimental studies on ALBs' mechanisms in MPS-III has led clinicians to adopt symptomatic treatments, such as antipsychotics, which are used for non-genetic neuropsychiatric disorders.
View Article and Find Full Text PDFNeurol Med Chir (Tokyo)
January 2025
Department of Neurosurgery, Tohoku University Graduate School of Medicine.
Pediatric patients with moyamoya disease frequently show rapid progression with a high risk of stroke. Indirect revascularization is widely accepted as a surgical treatment for pediatric moyamoya disease, but it does not augment cerebral blood flow immediately, which leaves patients at risk for stroke peri-operatively. This delay in flow augmentation may make adding direct bypass the better option.
View Article and Find Full Text PDFEnviron Res
January 2025
Department of Epidemiology, NUTRIM School for Translational Research in Metabolism, Maastricht University Medical Centre, P.O. Box 616, 6200 MD Maastricht, The Netherlands. Electronic address:
Prenatal exposure to air pollution has been linked to lower birth weight, yet the role of the placenta in this association is often overlooked. This study investigates whether placental characteristics act as moderators or mediators in the association between prenatal exposure to particulate matter (PM) and nitrogen dioxide (NO) and birth weight in twins. The study included 3340 twins (born 2002-2013) from the East Flanders Prospective Twin Survey.
View Article and Find Full Text PDFCrit Rev Oncol Hematol
January 2025
Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Republic of Korea. Electronic address:
Background: Despite numerous meta-analyses comparing the efficacy and safety of immunotherapy-based combination therapies, the optimal therapeutic combinations remain unclear. This study aims to evaluate the optimal application of all immunotherapy-based combination therapy for advanced/metastatic renal cell carcinoma, focusing on efficacy and safety.
Methods: We systemically searched the Web of Science, Cochrane Library, and PubMed for studies regarding the first-line immunotherapy-based combination therapy in patients with advanced or metastatic renal cell carcinoma until April 15, 2024.
J Infect
January 2025
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, United States.
Background: Pneumococcal conjugate vaccines (PCVs) introduced in childhood national immunization programs lowered vaccine-type invasive pneumococcal disease (IPD), but replacement with non-vaccine-types persisted throughout the PCV10/13 follow-up period. We assessed PCV10/13 impact on pneumococcal meningitis incidence globally.
Methods: The number of cases with serotyped pneumococci detected in cerebrospinal fluid and population denominators were obtained from surveillance sites globally.
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