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The analysis of foveal microvascular anomalies in retinopathy of prematurity after anti-vascular endothelial growth factor therapy using optical coherence tomography angiography.
BMC Ophthalmol
November 2024
Department of Ophthalmology, Peking University People's Hospital, Eye Disease and Optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, College of Optometry, Peking University Health Science Center, No. 11 Xizhimen South Street, Xicheng District, Beijing, China.
Background: To investigate the quantitative vascular and structural differences in the foveal region of the eyes in retinopathy of prematurity children with or without anti-vascular endothelial growth factor (VEGF) therapy and healthy children using optical coherence tomography angiography (OCTA).
Methods: This cross-sectional study analyzed 75 eyes from 44 subjects, categorized into four groups: ROP children treated with Conbercept or Ranibizumab, spontaneously regressed ROP, and healthy age-matched children. Using spectral-domain OCT and OCTA, we assessed parameters like central foveal thickness (CFT), foveal avascular zone (FAZ), superficial/deep capillary plexus (SCP/DCP), and choroidal vessel density (VD) at the fovea.
Clinical Presentation and Treatment Outcomes of Adult-Onset Coats Disease.
J Vitreoretin Dis
September 2024
Department of eyeSmart EMR & AEye, LV Prasad Eye Institute, Hyderabad, Telangana, India.
To study the clinical profile, treatment, and outcomes of patients 35 years or older diagnosed with Coats disease. A cross-sectional observational hospital-based study was performed. The study included 74 eyes diagnosed with adult-onset Coats disease.
View Article and Find Full Text PDFRetinal curvature in Chinese children with myopia measured by ultra-widefield swept-source optical coherence tomography.
Br J Ophthalmol
September 2024
Shanghai Eye Disease Prevention and Treatment Center, Shanghai, China
Aims: To quantitatively measure retinal curvature (RC) in children with myopia and explore its association with refractive status.
Methods: This cross-sectional study included participants aged 5-18 years who underwent comprehensive ocular examinations, including cycloplegic refraction and macula 24×20 mm optical coherence tomography (OCT) scans. RC was derived from OCT data using a three-dimensional reconstruction system.
EN FACE OPTICAL COHERENCE TOMOGRAPHY MORPHOLOGY OF MACULAR PUCKER CORRELATES WITH METAMORPHOPSIA: Possible Role of the Henle Fiber Layer.
Retina
September 2024
Doheny Eye Institute, University of California Los Angeles, Pasadena, California.
Purpose: To describe macular pucker contraction patterns with en face optical coherence tomography (OCT), to provide a correlation with metamorphopsia scores, and to discuss the protective role of the Henle fiber layer (HFL) against tangential traction.
Methods: Retrospective, institutional, observational, and consecutive case series. Clinical charts, M-charts scores, and structural and en face OCT imaging of patients diagnosed with macular pucker were reviewed.
In Vivo Assessment of Retinal Phenotypes in Axenfeld-Rieger Syndrome.
Invest Ophthalmol Vis Sci
April 2024
Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
Purpose: Axenfeld-Rieger syndrome (ARS) is characterized by ocular anomalies including posterior embryotoxon, iridocorneal adhesions, corectopia/iris hypoplasia, and developmental glaucoma. Although anterior segment defects and glaucoma contribute to decreased visual acuity, the role of potential posterior segment abnormalities has not been explored. We used high-resolution retinal imaging to test the hypothesis that individuals with ARS have posterior segment pathology.
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