Background: Aedes aegypti can transmit arboviruses worldwide, and Bacillus thuringiensis svar. israelensis (Bti)-based larvicides represent an effective tool for controlling this species. The safety of Bti and lack of resistance have been widely reported; however, little is known regarding the impact of the extensive use of these larvicides on the life traits of mosquitoes. Therefore, this study investigated biological parameters, including susceptibility to arbovirus, of an Ae. aegypti strain (RecBti) subjected to 29 generations of exposure to Bti compared with the RecL reference strain.
Methods: The biological parameters of individuals reared under controlled conditions were compared. Also, the viral susceptibility of females not exposed to Bti during their larval stage was analysed by oral infection and followed until 14 or 21 days post-infection (dpi).
Results: RecBti individuals did not display alterations in the traits that were assessed (fecundity, fertility, pupal weight, developmental time, emergence rate, sex ratio and haematophagic capacity) compared to RecL individuals. Females from both strains were susceptible to dengue serotype 2 (DENV-2) and Zika virus (ZIKV). However, RecBti females showed significantly higher rates of ZIKV infection compared with RecL females at 7 (90% versus 68%, Chi-square: χ = 7.27, df = 1, P = 0.006) and 14 dpi (100% versus 87%, Chi-square: χ = 7.69, df = 1, P = 0.005) and for dissemination at 7 dpi (83.3% versus 36%, Fisher's exact test: P < 0.0001, OR = 0.11, 95% CI 0.03-0.32). Quantification of DENV-2 and ZIKV viral particles produced statistically similar results for females from both strains.
Conclusions: Prolonged exposure of Ae. aegypti larvae to Bti did not alter most of the evaluated biological parameters, except that RecBti females exhibited a higher vector susceptibility for ZIKV. This finding is related to a background of Bti exposure for several generations but not to a previous exposure of the tested females during the larval stage. This study highlights mosquito responses that could be associated with the chronic exposure to Bti in addition to the primary larvicidal effect elicited by this control agent.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8317411 | PMC |
| http://dx.doi.org/10.1186/s13071-021-04880-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Diverse Self-Assembled Molecular Architectures Promoted by C-H···O and C-H···Cl Hydrogen Bonds in a Triad of α-Diketone, α-Ketoimine, and an Imidorhenium Complex: A Unified Analysis Based on XRD, NEDA, SAPT, QTAIM, and IBSI Studies.
ACS Omega
November 2024
Department of Chemistry, St. Paul's Cathedral Mission College, University of Calcutta, 33/1 Raja Rammohan Roy Sarani, Kolkata 700009, India.
X-ray structural elucidation, supramolecular self-assembly, and energetics of existential noncovalent interactions for a triad comprising α-diketone, α-ketoimine, and an imidorhenium complex are highlighted in this report. Molecular packing reveals a self-assembled 2D network stabilized by the C-H···O H-bonds for the α-diketone (benzil), and the first structural report of Brown and Sadanaga stressing on the prevalence of seems to be an oversimplified conjecture. In the α-ketoimine, the imine nitrogen atom undergoes intramolecular N···H interaction to render itself inert toward intermolecular C-H···N interaction and exhibits two types of C-H···O H-bonds in consequence to generate a self-assembled 2D molecular architecture.
View Article and Find Full Text PDFExposure to Zika and chikungunya viruses impacts aspects of the vectorial capacity of Aedes aegypti and Culex quinquefasciatus.
PLoS One
May 2024
Departamento de Entomologia, Instituto Aggeu Magalhães, Fundação Oswaldo Cruz (FIOCRUZ-PE), Recife, Pernambuco, Brasil.
Zika (ZIKV) and chikungunya (CHIKV) are arboviruses that cause infections in humans and can cause clinical complications, representing a worldwide public health problem. Aedes aegypti is the primary vector of these pathogens and Culex quinquefasciatus may be a potential ZIKV vector. This study aimed to evaluate fecundity, fertility, survival, longevity, and blood feeding activity in Ae.
View Article and Find Full Text PDFRhenium Tricarbonyl Complexes of Azodicarboxylate Ligands.
Molecules
November 2022
Department für Chemie, Institut für Anorganische Chemie, Mathematisch-Naturwissenschaftliche Fakultät, Universität zu Köln, Greinstrasse 6, D-50939 Köln, Germany.
The excellent π-accepting azodicarboxylic esters adcOR (R = Et, Pr, Bu, Bn (CH-CH) and Ph) and the piperidinyl amide derivative adcpip were used as bridging chelate ligands in dinuclear Re(CO) complexes [{Re(CO)Cl}(µ-adcOR)] and [{Re(CO)Cl}(µ-adcpip)]. From the adcpip ligand the mononuclear derivatives [Re(CO)Cl(adcpip)] and [Re(CO)(PPh)(µ-adcpip)]Cl were also obtained. Optimised geometries from density functional theory (DFT) calculations show and isomers for the dinuclear -Re(CO) complexes at slightly different energies but they were not distinguishable from experimental IR or UV-Vis absorption spectroscopy.
View Article and Find Full Text PDFPhotoinduced Processes in Rhenium(I) Terpyridine Complexes Bearing Remote Amine Groups: New Insights from Transient Absorption Spectroscopy.
Molecules
October 2022
Institute of Chemistry, University of Silesia, Szkolna 9, 40-006 Katowice, Poland.
Photophysical properties of two Re(I) complexes [ReCl(CO)(R-CH-terpy-κN)] with remote amine groups, -methyl-piperazinyl () and (2-cyanoethyl)methylamine (), were investigated. The complexes show strong absorption in the visible region corresponding to metal-to-ligand charge transfer (MLCT) and intraligand-charge-transfer (ILCT) transitions. The energy levels of MLCT and ILCT excited-states, and thus photoluminescence properties of and , were found to be strongly affected by the solvent polarity.
View Article and Find Full Text PDFA fundamental role of the solvent polarity and remote substitution of the 2-(4-R-phenyl)-1-imidazo[4,5-][1,10]phenanthroline framework in controlling the ground- and excited-state properties of Re(I) chromophores [ReCl(CO)(R-CH-imphen)].
Dalton Trans
October 2022
Institute of Chemistry, Faculty of Science and Technology, University of Silesia in Katowice, Szkolna 9, Poland.
A series of Re(I) carbonyl complexes with the 1-imidazo[4,5-][1,10]phenanthroline (imphen) ligand functionalized with electron-donating amine groups attached to the imidazole ring phenylene linkages were designed to investigate the impact of remote amine substituents on the ground- and excited-state properties of [ReCl(CO)(R-CH-imphen)]. The complexes [ReCl(CO)(R-CH-imphen)] belong to the family of [ReCl(CO)(diimine)] systems, but contrary to strongly related phenanthroline Re(I) carbonyl complexes with a rich history in coordination chemistry, they are really sparse. The effects of electron-rich N-donor groups in [ReCl(CO)(R-CH-imphen)] were fully studied with the use of cyclic voltammetry, absorbance and emission spectroscopy, and transient absorption spectroscopy, and they were simulated by density functional theory.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!