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When the Gleam of Obstruction Isn't Just Stones: A Case Report of Intraductal Papillary Neoplasm of the Bile Duct (IPNB) and the Role of Cholangioscopy in Its Management.
Cureus
December 2024
Gastroenterology and Hepatology, Aberdeen Royal Infirmary Hospital, Aberdeen, GBR.
Intraductal papillary neoplasm of the bile duct (IPNB) is a precursor lesion to biliary tract carcinoma. It is characterised by papillary growth within the bile ducts. The diagnosis and management of IPNB are challenging due to its varying presentations and overlapping features with other biliary diseases.
View Article and Find Full Text PDFSelection methods for endoscopic ultrasound‑guided biliary drainage cases that are appropriate for beginners.
Exp Ther Med
March 2025
Department of Gastroenterology, School of Medicine, Fukushima Medical University, Fukushima, Fukushima 960-1295, Japan.
Endoscopic ultrasound-guided biliary drainage (EUS-BD) is performed as a second drainage method when endoscopic retrograde cholangiopancreatography-guided biliary drainage fails. There are several severe adverse events in EUS-BD, and avoiding technical failure is desirable. Although EUS-BD is a skilled endoscopic treatment, the appropriate conditions for EUS-BD beginners are not well known.
View Article and Find Full Text PDFFistula in Crohn's disease: classification, pathogenesis, and treatment options.
Tissue Barriers
January 2025
Department of Gastroenterology and Hepatology, Virginia Tech Carilion School of Medicine (VTCSOM), Carilion Clinic, Roanoke, VA, USA.
Crohn's disease is a form of inflammation that affects the gastrointestinal (GI) tract. It is characterized by persistent inflammation in the gut, which can lead to the formation of abnormal connections called fistulas. These fistulas can occur between the GI tract and the abdominal cavity, adjacent organs, or the skin.
View Article and Find Full Text PDFElective thoracoscopic surgery for congenital lung malformations: what age to operate?
Eur J Pediatr
January 2025
Department of Pediatric Surgery, Shengjing Hospital of China Medical University, Shenyang, China.
Purpose: This study aimed to evaluate the characteristics of congenital lung malformations (CLMs) in patients from infancy to adulthood, and to determine the optimal timing for thoracoscopic surgery.
Methods: All patients with CLMs who underwent thoracoscopic surgery between 2017 and 2023 were retrospectively reviewed. The patients were divided into five age groups: 1-6 months, 6-12 months, 1-4 years, 4-16 years, and >16 years.
Frequency and Molecular Characteristics of Mismatch Repair-deficient Status among Multiple Synchronous Colorectal Cancers.
J Anus Rectum Colon
January 2025
Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan.
Objectives: Mismatch repair (MMR)-deficient (dMMR) colorectal cancer (CRC) have been largely categorized into three subtypes: methylated, Lynch syndrome (LS)-associated, and Lynch-like syndrome (LLS)-associated. No studies have examined the prevalence and subtypes of synchronously diagnosed dMMR CRCs in detail. Therefore, this study aimed to examine the frequency and molecular characteristics of the dMMR status among multiple synchronous CRCs to clarify the clinical significance of identifying patients with such tumors.
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