Purpose: To analyze which method of judgment, auditory- perceptual (PAJ) of audios or perceptual-visual judgment (PVJ) (ultrasound images), is more sensitive to detect gradual productions between the class of deaf coronal fricatives and check if there is a correlation between these forms of judgment.
Method: Audio and video files of language ultrasound (LUS) related to the production of the words "frog" and "key", of 11 children, between 6 and 12 years old, with atypical speech production, were selected from a bank data and edited for judgments. After instruction and prior training, 20 judges should choose, immediately upon presentation of the stimulus (auditory or visual), one of three options arranged on the computer screen. In PAJ the options were: correct, incorrect or gradient production, while in PVJ the options were images corresponding to the production of [s], [∫] or undifferentiated. The presentation time of the stimuli and the reaction time were automatically controlled by the PERCEVAL software.
Results: PVJ provided a higher percentage of identification of gradient stimuli and a shorter reaction time in performing the task compared to PAJ, both statistically significant. Spearman's correlation test did not show statistical significance between PAJ and PVJ responses, nor for reaction time.
Conclusion: PVJ using US images proved to be the most sensitive method for detecting gradient production in the production of fricatives [s] and [∫], and can be used as a complementary method to PAJ in speech analysis.
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http://dx.doi.org/10.1590/2317-1782/20202020197 | DOI Listing |
Brain functional connectivity patterns exhibit distinctive, individualized characteristics capable of distinguishing one individual from others, like fingerprint. Accurate and reliable depiction of individualized functional connectivity patterns during infancy is crucial for advancing our understanding of individual uniqueness and variability of the intrinsic functional architecture during dynamic early brain development, as well as its role in neurodevelopmental disorders. However, the highly dynamic and rapidly developing nature of the infant brain presents significant challenges in capturing robust and stable functional fingerprint, resulting in low accuracy in individual identification over ages during infancy using functional connectivity.
View Article and Find Full Text PDFKawasaki disease (KD) is a leading cause of acquired heart disease in children, often resulting in coronary artery complications such as dilation, aneurysms, and stenosis. While intravenous immunoglobulin (IVIG) is effective in reducing immunologic inflammation, 10-15% of patients do not respond to initial therapy, and some show resistance even after two consecutive treatments. Predicting which patients will not respond to these two IVIG treatments is crucial for guiding treatment strategies and improving outcomes.
View Article and Find Full Text PDFJ Org Chem
January 2025
Graduate School of Science, Nagoya University, Nagoya 464-8602, Japan.
During the recent development of machine-learning (ML) methods for organic synthesis, the value of "failed experiments" has increasingly been acknowledged. Accordingly, we have developed an exhaustive database comprising 300 entries of experimental data obtained by performing ruthenium-catalyzed hydrogenation reactions using 10 ketones as substrates and 30 phosphine ligands. After evaluating the predictive performance of ML models using the constructed database, we conducted a virtual screening of commercially available phosphine ligands.
View Article and Find Full Text PDFEndocrinol Diabetes Metab
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Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran.
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Introduction Urinary tract infections (UTIs) are one of the most common bacterial infections encountered in community and healthcare settings. Increasing antimicrobial resistance patterns worldwide have limited the treatment options available. Overuse of carbapenems which were considered as the last resort for multi-drug resistant UTIs over the past decade has led to the emergence of carbapenem-resistant Enterobacterales (CRE).
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