AI Article Synopsis
- Bovine adenovirus 7 (BAdV-7) isolate SD18-74 was identified from calves' lung tissue in South Dakota and has a 30,043-nucleotide genome typical of the Atadenovirus genus.
- The sequence of SD18-74 shows over 99% similarity with two Japanese BAdV-7 strains and 74.9% similarity with the ovine adenovirus 7 strain OAV287.
- SD18-74 was able to grow effectively in both bovine and ovine nasal cells, with a preference for bovine cells, suggesting its genomic and biological traits warrant its classification into a new species within the Atadenovirus genus.
Article Abstract
The bovine adenovirus 7 (BAdV-7) isolate SD18-74 was recovered from lung tissue of calves in South Dakota. The 30,043-nucleotide (nt) genome has the typical organization of Atadenovirus genus members. The sequence shares over 99% nt sequence identity with two Japanese BAdV-7 sequences, followed by 74.9% nt sequence identity with the ovine adenovirus 7 strain OAV287, a member of the species Ovine atadenovirus D. SD18-74 was amplified in both bovine and ovine primary nasal turbinate cells, demonstrating greater fitness in bovine cells. The genomic and biological characteristics of BAdV-7 SD18-74 support the inclusion of the members of the BAdV-7 group in a new species in the genus Atadenovirus.
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| http://dx.doi.org/10.1007/s00705-021-05184-x | DOI Listing |
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