Use of PCSK9 Inhibitors in Solid Organ Transplantation Recipients.

JACC Case Rep

Center for Preventive Cardiology, Knight Cardiovascular Institute, Oregon Health and Science University, Portland, Oregon.

Published: March 2020

Standard lipid-lowering therapies in solid organ transplantations pose challenges due to interactions with immunosuppressants. Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) represent a new class of lipid-lowering therapies with potential promise in this population. We describe PCSK9i as an efficacious and safe option for management of hypercholesterolemia in solid organ transplantations. ().

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8311616PMC
http://dx.doi.org/10.1016/j.jaccas.2019.09.026DOI Listing

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