Complete Regression of Primary Cardiac Lymphoma With Dose-Attenuated R-CVP Chemotherapeutic Regimen.

JACC Case Rep

Departments of Cardiology and Medicine, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Slough, Berkshire, United Kingdom.

Published: October 2019

An elderly man was found to have a large right atrioventricular mass and pericardial effusion. He was diagnosed and treated as having primary cardiac lymphoma. A dose-attenuated chemotherapy regimen of rituximab, cyclophosphamide, vincristine, and prednisolone, with a cytoreductive pre-phase, afforded complete regression of disease with resolution of the patient's symptoms, and without deterioration in cardiac function or immunosuppression. The patient remains well 12 months after presentation. ().

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289086PMC
http://dx.doi.org/10.1016/j.jaccas.2019.06.033DOI Listing

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