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  • The review focuses on episode-based bundled payment models for hand surgery as a means to reduce healthcare costs and improve patient care.
  • Traditional fee-for-service models are ineffective in promoting collaboration among healthcare providers, while bundled payments encourage team-based approaches and resource optimization.
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Background: Contingency management (CM), an incentive-based intervention to encourage target behaviors, effectively promotes medication adherence. However, efforts to extend CM to HIV pre-exposure prophylaxis (PrEP) have been lacking. As part of a randomized clinical trial to promote HIV Prevention among people who inject drugs (PWID), we examined the readiness of staff in community-based organizations serving PWID to implement CM for PrEP uptake and adherence in this population.

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Can mathematical proofs be employed for the solution of fundamental molecular-level problems in biology? Recently, I mathematically tackled complex mechanistic problems arising during the synthesis of the universal biological currency, adenosine triphosphate (ATP) by the FF-ATP synthase, nature's smallest rotary molecular motor, using graph-theoretical and combinatorial approaches for the membrane-bound F and water-soluble F domains of this fascinating molecule (see Nath in Theory Biosci 141:249‒260, 2022 and Theory Biosci 143:217‒227, 2024). In the third part of this trilogy, I investigate another critical aspect of the molecular mechanism-that of coupling between the F and F domains of the ATP synthase mediated by the central γ-subunit of nanometer diameter. According to Nath's torsional mechanism of energy transduction and ATP synthesis the γ-subunit twists during ATP synthesis and the release of stored torsional energy in the central γ-stalk causes conformational changes in the catalytic sites that lead to ATP synthesis, with 1 ATP molecule synthesized per discrete 120° rotation.

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Exploring scanning electrochemical probe microscopy in single-entity analysis in biology: Past, present, and future.

Biosens Bioelectron

December 2024

Hubei University of Science & Technology, Xianning Medical College, Xianning, Hubei, 437100, China. Electronic address:

Scanning Electrochemical Probe Microscopy (SEPM) shows significant potential promise for analyzing localized electrochemical activity at biological interfaces of single entities. Utilizing various SEPM probe manipulations allows real-time monitoring of the morphology and physiological activities of single biological entities, offering vital electrochemical insights into biological processes. This review focuses on the application of five SEPM techniques in imaging single biological entities, highlighting their unique advantages in the observation and quantitative evaluation of biological morphology.

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Screening and response for intimate partner violence (IPV) is recommended for women in priority populations and is implemented in health services across diverse jurisdictions. Most women experiencing IPV strongly support screening, however this is untested with refugee women in resettlement contexts. Around one third of refugee women in Australia experience IPV and face multiple post-migration challenges.

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