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Article Abstract
Introduction: The association between proton pump inhibitors' (PPIs) use and mortality remains unclear.
Methods: This was a prospective analysis of 440,840 UK residents and 13,154 deaths. We evaluated the associations with multivariate Cox regression.
Results: After adjusting for confounders, such as over health status and longstanding diseases, the regular use of PPIs was not associated with an increased risk of all-cause mortality and mortality due to neoplasms, circulatory system diseases, respiratory system diseases, digestive system diseases, external causes, and other causes.
Discussion: Regular use of PPIs was not associated with an increased risk of all-cause and cause-specific mortality.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560155 | PMC |
| http://dx.doi.org/10.14309/ajg.0000000000001377 | DOI Listing |
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