AI Article Synopsis
- The study addresses the global health issue of bacterial infections on surfaces by developing a specialized wound dressing.
- The researchers created a nanocomposite using polycaprolactone and hydrophobic carbon quantum dots (hCQDs), utilizing both solvent casting and electrospinning techniques.
- The nanocomposite demonstrated strong antibacterial properties, effectively eliminating both Gram-positive and Gram-negative bacteria when exposed to blue light, indicating potential for improved wound care solutions.
Article Abstract
Inhabitation of various types of bacteria on different surfaces causes vital health problems worldwide. In this work, a wound dressing defeating bacterial infection had been fabricated. The antibacterial effect of polycaprolactone and hydrophobic carbon quantum dots (hCQDs) based nanocomposite has been presented. The nanocomposite was fabricated both via solvent casting and electrospinning method. Nanocomposites with and without hCQDs had been investigated. A detailed study on their morphology and surface properties were performed by scanning electron microscopy, atomic force microscopy and Raman spectroscopy. Prepared nanocomposites had been evaluated by the contact angle, UV-Vis spectroscopy, electron paramagnetic resonance spectroscopy, and antibacterial activity. It was found that nanocomposites were able to produce singlet oxygen upon blue light irradiation at 470 nm, and they were effective in the eradication of Gram positive (Staphylococcus aureus, Listeria monocytogenes) and Gram negative (Escherichia coli, Klebsiella pneumoniae) bacteria.
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| http://dx.doi.org/10.1016/j.pdpdt.2021.102455 | DOI Listing |
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